Figure 3From: Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactamsHeterogeneity of volume of distribution in litres of β-lactam antibiotics in ICU patients. Open circles: volume of distribution in healthy volunteers [44, 51, 89–92]; filled squares: weighted means of volume of distribution in the studies; straight lines: ranges of the means of volume of distribution in the studies.Back to article page