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Table 3 Univariate and multivariate logistic regression analysis of factors associated with mortality in diabetic and non-diabetics

From: sRAGE in diabetic and non-diabetic critically ill patients: effects of intensive insulin therapy

  Diabetic Non-diabetic
  Univariate Multivariate Univariate Multivariate
Variable Estimate P Estimate P Estimate P Estimate P
Age (years) 0.012 NS    0.036 0.04   NS
Gender 0.464 NS    0.875 NS   
BMI -0.075 NS    -0.083 NS   
APACHE II score 0.100 NS    0.124 0.02   NS
SOFA score * 0.345 0.02 0.357 0.03 0.009 NS   
sRAGE (pg/ml) 0.0004 NS    -0.00008 NS   
IL-6 (pg/ml) 0.00003 NS    0.001 NS   
Thrombomodulin (ng/ml) 0.004 NS    0.007 NS   
HMGB-1 (ng/ml) -0.321 NS    0.046 NS   
Creatinine (μmol/L) -0.002 NS    0.003 NS   
Creatinine clearance (ml/minute) -0.0096 NS    -0.028 0.01 -0.058 NS
Blood glucose (mmol/L)* 0.196 NS    0.514 0.003   0.03
PaO2/FiO2 (mm Hg) 0.0009 NS    -0.006 NS   
INR * 2.753 0.01 2.328 0.04 3.176 0.02   NS
  1. * P < 0.05 for both uni-and multivariate analysis
  2. APACHE, Acute Physiologic Score and Chronic Health Evaluation; HMGB-1, high mobility group box-1; IL-6, interleukin-6; INR, international normalized ratio; PaO2/FIO2, ratio of partial pressure of oxygen to the fraction of inspired oxygen; SOFA, Sequential Organ Failure Assessment; sRAGE, soluble receptor for advanced glycation end-products.