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Table 1 Baseline characteristics and outcome of diabetic and non-diabetic patients admitted in ICU

From: sRAGE in diabetic and non-diabetic critically ill patients: effects of intensive insulin therapy

  Diabetic Non-Diabetic  
  IIT
(n= 16)
CIT
(n= 17)
IIT
(n= 27)
CIT
(n= 16)
P
Age (years) 66.1 ± 3.5 65.9 ± 2.0 49.3 ± 4.5 43.4 ± 5.2 < 0.0001
Sex, male: female 6:10 7: 10 22:5 13:3 0.0001
BMI 31.2 ± 1.6 33.8 ± 2.6 25.1 ± 0.8 26.6 ± 1.0 0.0003
APACHE II score 28.6 ± 1.9 29.4 ± 1.7 22.3 ± 1.6 24.1 ± 2.0 0.001
Blood glucose (mmol/L) 15.0 ± 1.1 13.4 ± 0.9 11.1 ± 0.7 10.0 ± 0.4 < .0001
Creatinine (μmol/l) 178 ± 31 222 ± 47 119 ± 20 144 ± 41 0.14
Creatinine clearance (ml/min) 55 ± 10 52 ± 9 90 ± 9 95 ± 15 0.007
Admission category      
   Medical 16 16 21 14 0.15
   Surgical 0 1 6 2 0.15
SOFA score (Day 1) 9.3 ± 0.7 10.9 ± 0.8 8.3 ± 0.6 10.0 ± 0.7 0.11
SOFA score (Day 3)
SEPSIS
7.4 ± 3.0 8.6 ± 3.7 7.0 ± 4.0 8.9 ± 2.6 0.25
ICU acquired sepsis 9 7 11 8 0.89
Length of hospital stay (days) 64.4 ± 14.4 42.6 ± 8.8 48.4 ± 10.0 48.3 ± 9.5 0.77
ICU mortality, no. 4 3 6 2 0.84
Hospital mortality, no. 9 11 7 3 0.001
  1. Values represent mean (SE) in age, BMI, Acute Physiologic Score and Chronic Health Evaluation (APACHE II) score, blood glucose, and Sequential Organ Failure Assessment (SOFA) score on admission to ICU. P-values represent the comparison between diabetic (n = 33) and non-diabetic patients (n = 43). Creatinine clearance = (140 - age(yr))*weight(kg))/(72*serum Cr(mg/dL)) (multiply by 0.85 for women) [34].