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Table 1 Baseline characteristics and outcome of diabetic and non-diabetic patients admitted in ICU

From: sRAGE in diabetic and non-diabetic critically ill patients: effects of intensive insulin therapy

 

Diabetic

Non-Diabetic

 
 

IIT

(n= 16)

CIT

(n= 17)

IIT

(n= 27)

CIT

(n= 16)

P

Age (years)

66.1 ± 3.5

65.9 ± 2.0

49.3 ± 4.5

43.4 ± 5.2

< 0.0001

Sex, male: female

6:10

7: 10

22:5

13:3

0.0001

BMI

31.2 ± 1.6

33.8 ± 2.6

25.1 ± 0.8

26.6 ± 1.0

0.0003

APACHE II score

28.6 ± 1.9

29.4 ± 1.7

22.3 ± 1.6

24.1 ± 2.0

0.001

Blood glucose (mmol/L)

15.0 ± 1.1

13.4 ± 0.9

11.1 ± 0.7

10.0 ± 0.4

< .0001

Creatinine (μmol/l)

178 ± 31

222 ± 47

119 ± 20

144 ± 41

0.14

Creatinine clearance (ml/min)

55 ± 10

52 ± 9

90 ± 9

95 ± 15

0.007

Admission category

     

   Medical

16

16

21

14

0.15

   Surgical

0

1

6

2

0.15

SOFA score (Day 1)

9.3 ± 0.7

10.9 ± 0.8

8.3 ± 0.6

10.0 ± 0.7

0.11

SOFA score (Day 3)

SEPSIS

7.4 ± 3.0

8.6 ± 3.7

7.0 ± 4.0

8.9 ± 2.6

0.25

ICU acquired sepsis

9

7

11

8

0.89

Length of hospital stay (days)

64.4 ± 14.4

42.6 ± 8.8

48.4 ± 10.0

48.3 ± 9.5

0.77

ICU mortality, no.

4

3

6

2

0.84

Hospital mortality, no.

9

11

7

3

0.001

  1. Values represent mean (SE) in age, BMI, Acute Physiologic Score and Chronic Health Evaluation (APACHE II) score, blood glucose, and Sequential Organ Failure Assessment (SOFA) score on admission to ICU. P-values represent the comparison between diabetic (n = 33) and non-diabetic patients (n = 43). Creatinine clearance = (140 - age(yr))*weight(kg))/(72*serum Cr(mg/dL)) (multiply by 0.85 for women) [34].
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Critical Care

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