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Table 3 Univariable and multivariable analyses of characteristics associated with hospital mortality

From: Admissions to intensive care unit of HIV-infected patients in the era of highly active antiretroviral therapy: etiology and prognostic factors

Characteristics Univariable analysis Multivariable analysis
  Odds ratio
(95% CI)
P
value
Odds ratio
(95% CI)
P
value
Age (per 10-year increase) 1.15 (0.88-1.51) 0.3   
Male 2.03 (0.58-7.10) 0.27   
HIV risk factor   0.8   
   MSM reference    
   Bisexual 0.78 (0.16-3.82) 0.8   
   Injecting drug use 0.62 (0.20-1.96) 0.4   
   Transfusion-related 2.08 (0.18-24.31) 0.6   
   Heterosexual/other/unknown 1.12 (0.53-2.37) 0.8   
HIV-related characteristics     
   Newly diagnosed HIV infection 1.56 (0.79-3.08) 0.205   
   Prior HAART at hospital admission 0.78 (0.39-1.57) 0.5   
   HAART initiated during ICU stay 1.05 (0.32-3.44) 0.9   
   HAART use in ICU 1.12 (0.56-2.24) 0.7   
   HIV viral load (per 1-log copies/ml increase)a 1.025 (0.83-1.26) 0.8   
   CD4 lymphocyte count (per 10-cells/mm3 decrease)b 1.033 (1.004-1.063) 0.027 1.036 (1.003-1.069) 0.033
Admission diagnosis     
   Respiratory failure 0.99 (0.50-1.95) 1.0   
   Interstitial pneumonitis with ground glass opacity 0.78 (0.39-1.57) 0.5   
   Sepsis (including bacterial pneumonia) 2.25 (1.08-4.69) 0.03 2.91 (1.11-7.62) 0.029
Hospitalization to ICU admission > 24 hours 2.72 (1.23-6.01) 0.013 2.21 (0.90-5.47) 0.085
Albumin (per 1 g/dl decrease) c 1.69 (1.04-2.74) 0.034 1.31 (0.74-2.34) 0.36
  1. The goodness of fit (Hossmer-Lemeshow Chisquare P value) was 0.619. 14 patients were not included in the multivariable model because of missing data.
  2. aData were available for 121 ICU admissions.
  3. bData were available for 129 ICU admissions.
  4. cData were available for 127 ICU admissions.
  5. CI, confidence interval; HAART, highly active antiretroviral therapy; MSM, men who have sex with men.