Table 1 Hemodynamic and renal findings during baseline, development (DS) and intervention sepsis periods in the CG and AG groups
From: Cardiovascular effects of β-blockade in a sheep model of severe sepsis
Group | Baseline period | Development sepsis period (DS) | Sepsis intervention period | P value | |
|---|---|---|---|---|---|
CO | CG | 3.68 (0.29) | 3.68 (0.29) | 4.12 (0.29) | <0.001 |
AG | 3.21 (0.22) | 3.21 (0.22) | 5.63 (0.53) | ||
HR | CG | 66.0 (6.5) | 66.0 (6.5) | 108.8 (8.6) | <0.001 |
AG | 59.7 (6.4) | 59.7 (6.4) | 111.6 (8.4) | ||
MAP | CG | 93.7 (5.1) | 102.5 (3.6) | 86.1 (4.1) | 0.035 |
AG | 96.3 (5.0) | 102.5 (3.8) | 81.5 (4.3) | ||
RBF | CG | 217.3 (14.8) | 217.3 (14.8) | 324.8 (19.7) | 0.194 |
AG | 214.7 (19.9) | 214.7 (19.9) | 292.3 (27.4) | ||
UO | CG | 31.1 (7.1) | 84.1 (20.4) | 22.1 (4.8) | 0.097 |
AG | 34.8 (7.0) | 52.3 (17.4) | 16.8 (11.0) | ||
TPC | CG | 38.2 (3.4) | 38.9 (3.4) | 63.9 (6.8) | 0.084 |
AG | 34.3 (3.1) | 37.3 (3.2) | 51.4 (6.8) | <0.001 | |
SV | CG | 51.4 (3.7) | 39.1 (3.6) | 35.5 (8.2) | 0.147 |
AG | 51.2 (4.6) | 36.7 (3.5) | 39.6 (3.6) | ||
RVC | CG | 2.39 (0.18) | 3.26 (0.26) | 3.74 (0.41) | 0.55 |
AG | 2.23 (0.16) | 2.88 (0.26) | 3.53 (0.44) |