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Table 1 abstract P34

From: Sepsis-induced lung fibrosis in baboons is reduced by the treatment with a complement inhibitor

 

E. coli

E. coli+ CS T+5

 

Modified genes

 

Modified genes

 
 

Up

Down

Total

P value

Up

Down

Total

P value

Fibroblast transformation

32

10

42

1.41 × 10-6

12

69

81

1.09 × 10-7

Connective tissue disorder

133

59

192

2.62 × 10-5

92

341

434

3.1 × 10-7

Chemotaxis

39

13

52

5.0 × 10-3

31

92

123

1.98 × 10-5

Cell migration

95

40

135

2.11 × 10-5

80

250

330

9.36 × 10-8

Cell proliferation

187

70

257

2.67 × 10-8

118

466

584

5.83 × 10-13

Fibroblast proliferation

23

7

30

4.80 × 10-3

10

62

72

5.56 × 10-6

  1. CS T+5, compstatin-treated animals at T + 5 hours.