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Table 1 abstract P34

From: Sepsis-induced lung fibrosis in baboons is reduced by the treatment with a complement inhibitor

  E. coli E. coli+ CS T+5
  Modified genes   Modified genes  
  Up Down Total P value Up Down Total P value
Fibroblast transformation 32 10 42 1.41 × 10-6 12 69 81 1.09 × 10-7
Connective tissue disorder 133 59 192 2.62 × 10-5 92 341 434 3.1 × 10-7
Chemotaxis 39 13 52 5.0 × 10-3 31 92 123 1.98 × 10-5
Cell migration 95 40 135 2.11 × 10-5 80 250 330 9.36 × 10-8
Cell proliferation 187 70 257 2.67 × 10-8 118 466 584 5.83 × 10-13
Fibroblast proliferation 23 7 30 4.80 × 10-3 10 62 72 5.56 × 10-6
  1. CS T+5, compstatin-treated animals at T + 5 hours.