Lung Function and Organ Dysfunctions in 178 Patients Requiring Mechanical Ventilation During The 2009 Influenza A (H1N1) Pandemic

Table 4 Characteristics of patients receiving non-invasive ventilation on admission, and comparison to those receiving invasive ventilation

	NIV (n= 49)	Non-NIV (n= 129)	P
Proportion of the entire population	28%	72%
Age (years)	40 ± 16	44 ± 15	0.26
Gender (male)	25 (51%)	73 (57%)	0.51
APACHE II	16 ± 6	19 ± 7	0.01
PaO₂/FIO₂ day0	129 (70 to 173)	141 (92 to 217)	0.12
PCO₂ day0	42 (37 to 55)	42 (34 to 51)	0.23
COPD999	6/49 (12%)	22/129 (17%)	0.24
Asthma	2/49 (4%)	8/129 (6%)	0.58
CHF	1/49 (2%)	9/129 (7%)	0.20
Pregnancy	5/48 (10%)	11/128 (9%)	0.71
Immunosupression	3/49 (6%)	26/129 (20%)	0.03
Obesity¹	12/49 (24%)	34/129 (26%)	0.80
Hospital mortality	19 (39%)	66 (51%)	0.14
Total duration of mechanical ventilation (days)²	12 (6 to 21)	10 (6 to 16)]	0.15
LOS_ICU	15 (8 to 25)	11 (7 to 17)	0.06
LOS_HOSPITAL	19 (11 to 25)	16 (8 to 23)	0.06

CHF, chronic heart failure; COPD, chronic obstructive pulmonary disease; LOS_ICU, length of stay at the ICU, in days; LOS_HOSPITAL, length of stay at the hospital, in days; NIV, non-invasive ventilation
¹ Obesity was defined as a BMI > 30
² Refers to the sum of the duration of NIV plus the duration of invasive ventilation.

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