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Table 2 Variables related to mechanical ventilation in all patients, and comparison between survivors and non-survivors.

From: Lung Function and Organ Dysfunctions in 178 Patients Requiring Mechanical Ventilation During The 2009 Influenza A (H1N1) Pandemic

  Day 0 Day 3 Day 7 Day 10
  All S NonS P All S NonS P All S NonS P All S NonS P
N 178 93 85   152 89 63   129 80 42   73 38 35  
Tidal volume (ml/kg of IBW) 7.8 ± 2 8.0 ± 2 7.7 ± 2 .35 7.9 ± 2 8.0 ± 2 7.8 ± 2 .46 7.9 ± 2 8.2 ± 2 7.5 ± 1 .02 8.1 ± 2 8.3 ± 2 7.9 ± 2 .35
Plateau pressure (cmH2O) 26 ± 7 25 ± 6 27 ± 8 .09 24 ± 7 24 ± 6 26 ± 8 .10 24 ± 7 23 ± 6 27 ± 8 .01 25 ± 8 24 ± 7 26 ± 8 .16
PEEP. (cm H2O) 10 (7 to 14) 10 (7 to 14) 10 (8 to 14) .34 10 (7 to 14) 10 (7 to 12) 12 (7 to 14) .05 10 (6 to 14) 8 a (5 to 12) 12 (8 to 15) .003 10 (6 to 14) 8 b (6 to 12) 12 (8 to 15) .008
Driving Pressure (cm H2O) 16 ± 6 15 ± 5 17 ± 6 ..05 15 ± 6 14 ± 5 16 ± 6 .16 15 ± 6 14 ± 5 16 ± 7 .26 15 ± 7 14 ± 5 16 ± 8 .21
Respiratory rate (cycles/min) 21 ± 5 21 ± 5 21 ± 4 .66 21 ± 5 20 ± 4 22 ± 5 .22 21 ± 5 20 ± 4 22 ± 5 .15 20 ± 6 20 ± 5 23 ± 6 .03
PaO2/FIO2 136 (85 to 204) 146 (110 to 215) 125 (71 to 197) .02 178 a (125 to 251) 220 a (156 to 287) 134 (84 to 185) < 0.001 195 a (142 to 260) 230 a (172 to 292) 144 (88 to 190) < 0.001 172 a (109 to 235) 212 a (164 to 270) 123 (80 to 160) < 0.001
FIO2 (%) 80 (25 to 100) 70 (50 to 100) 100 (70 to 100) < 0.001 60 a (40 to 70) 50 a (40 to 60) 65 a (50 to 100) < 0.001 50 a (40 to 65) 50 a (40 to 55) 60a (45 to 85) < 0.001 50 a (41 to 70) 47 a (40 to 50) 80 a (50 to 100) < 0.001
  1. Data are presented as means ± standard deviations, and medians and (IQR)
  2. Vt, Tidal volume. IBW, predicted body weight. S, Survivors. NonS, Non-survivors. P, Intergroup comparisons (between survivors vs. non-survivors) at each day are shown.
  3. For intragroup comparisons over time: Days 3, 7 and 10 are compared to Day 0 values, in all patients, in survivors and in non-survivors.
  4. a P <.001; b P <.01