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Table 3 Comparison of two different cut-off points of plasma cell-free DNA for prediction of 90-day mortality

From: Plasma cell-free DNA in patients needing mechanical ventilation

Cut-off point, GE/ml 12,000 (Saukkonen 2008 [6]) 16,000 (present study)
Sensitivity 0.60 (0.53 to 0.68) 0.53 (0.45 to 0.60)
Specificity 0.55 (0.50 to 0.60) 0.69 (0.65 to 0.74)
Positive likelihood ratio 1.33 (1.13 to 1.57) 1.72 (1.40 to 2.11)
Odds ratio unadjusted 1.84 (1.28 to 2.65) 2.52 (1.31 to 4.83)
Odds ratio adjusted 1.39 (0.89 to 2.16) 2.22 (1.41 to 3.48)
  1. Data (at admission) presented with 95% confidence intervals
  2. GE, genome equivalents