Table 1 Baseline patient characteristicsa
From: Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock
| Demographics | Data (N= 14) |
|---|---|
| Age, years | 55 (47 - 62) |
| Females, n (%) | 9 (64) |
| Race, n (%) | |
| African-American | 3 (21) |
| Caucasian | 11 (79) |
| Comorbidities, n (%) | |
| Diabetes | 2 (14) |
| Hypertension | 8 (57) |
| Chronic obstructive pulmonary disease | 2 (14) |
| Coronary artery disease | 2 (14) |
| Congestive heart failure | 3 (21) |
| Renal insufficiency or end-stage renal disease | 4 (29) |
| Initial vital signs | |
| Temperature (°F) | 98.9 (97.0 - 100.0) |
| MAP (mmHg) | 64 (54 - 83) |
| Heart rate (bpm) | 99 (88 - 112) |
| Respiratory rate (breaths/minute) | 20 (16 - 23) |
| Initial laboratory data | |
| Sodium (mEq/L) | 140 (137 - 140) |
| Potassium (mEq/L) | 3.8 (3.1 - 4.2) |
| Bicarbonate (mEq/L) | 19 (16 - 24) |
| Creatinine (mg/dL) | 1.5 (0.9 - 3.5) |
| INR | 1.2 (1.2 - 1.5) |
| AST (IU/L) | 29 (7 - 35) |
| ALT (IU/L) | 29 (19 - 45) |
| White blood cells (1 × 103/μL) | 10.5 (6 - 16) |
| Hematocrit (%) | 31 (29 - 34) |
| Platelets (1 × 103/μL) | 196 (164 - 302) |
| Arterial blood gas | |
| pH | 7.36 (7.29 - 7.42) |
| PaCO2 (mmHg) | 38 (30 - 51) |
| PaO2 (mmHg) | 101 (75 - 113) |
| Lactate (mmol/L) | 2.1 (1.4 - 2.4) |
| CoQ10 data | |
| CoQ10 (μmol/L) | 0.49 (0.26 - 0.62) |
| LDL (mg/dL) | 42 (35 - 61) |
| CoQ10:LDL ratio | 101 (82 - 150) |