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Table 4 Changes in urine hepcidin levels adjusted to urine creatininea

From: Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study

Urine hepcidin/urine creatinine

AKI (n= 9)

No AKI (n= 91)

P value

Δ 6 to 0 hours, ng/mg

1,079 (85 to 2,195)

4,085 (1,998 to 8,736)

<0.001

Δ 6 to 0 hours, %

626 (108 to 1,541)

1,444 (867 to 3,269)

0.016

Δ 24 to 0 hours, ng/mg

1,142 (344 to 3,379)

2,821 (1,266 to 6,482)

0.119

Δ 24 to 0 hours, %

925 (270 to 1,825)

939 (338 to 2,458)

0.717

Δ 24 to 6 hours, ng/mg

325 (-397 to 1,959)

-1,051 (-4,350 to 1,531)

0.079

Δ 24 to 6 hours, %

139 (-29 to 235)

-33 (-71 to 71)

0.02

  1. aAKI, acute kidney injury. Data are medians (25th to 75th percentiles). Urine hepcidin/urine creatinine 6 hours to 0 hours for AKI: area under the curve receiver operating characteristic curve 0.88 (0.79 to 0.98) (P < 0.001), sensitivity 75%, specificity 87%, cutoff 1,320 ng/mg.