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Table 2 Interventions and outcomesa

From: Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study

 

All patients

Excluding patients with preoperative CKD

Variables

AKI ( n = 9)

No AKI ( n = 91)

P value

AKI ( n = 5)

No AKI ( n = 69)

P value

CABG surgery, n (%)

2 (22.2%)

17 (18.7%)

0.68

1 (20.0%)

13 (18.8%)

>0.99

Valve surgery, n (%)

4 (44.5%)

46 (50.5%)

>0.99

2 (40.0%)

37 (53.6%)

0.66

CABG and valve surgery, n (%)

3 (33.3%)

21 (23.1%)

0.68

2 (40.0%)

14 (20.3%)

0.29

Thoracic aortic surgery, n (%)

0 (0.0%)

7 (7.7%)

>0.99

0 (0.0%)

5 (7.3%)

>0.99

Previous cardiothoracic operation, n (%)

2 (22.2%)

26 (28.6%)

>0.99

1 (20.0%)

23 (33.3%)

>0.99

Duration of bypass, minutes

125 (100 to 172)

119 (91 to 158)

0.62

109 (80 to 146)

119 (90 to 156)

0.57

Fluid balanceb, mL

4,980 (3,000 to 16,200)

3,100 (1,690 to 4,660)

0.035

4,920 (450 to 16,200)

3,100 (1,260 to 4,800)

0.4

Furosemideb, n (%)

9 (100%)

84 (92.3%)

0.39

5 (100.0%)

63 (91.3%)

>0.99

Furosemideb, mg

130 (60 to 460)

50 (20 to 90)

0.003

160 (35 to 672)

45 (20 to 70)

0.05

Vasopressor useb, n (%)

7 (77.8%)

65 (71.4%)

0.69

5 (100.0%)

49 (71.0%)

0.32

Inotrope useb, n (%)

8 (88.9%)

51 (63.7%)

0.13

4 (80.0%)

45 (65.2%)

0.66

Blood transfusionb, n (%)

8 (88.9%)

52 (57.1%)

0.06

4 (80.0%)

39 (56.5%)

0.39

Blood transfusionb, mL

1,000 (500 to 6,380)

500 (0 to 500)

0.005

1,250 (250 to 6,800)

250 (0 to 500)

0.048

LOS in hospital, days

14 (8 to 19)

9 (7 to 14)

0.024

14 (8 to 19)

9 (7 to 14)

0.48

Need for RRT, n (%)

3 (33.3%)

2 (2.2%)

0.005

2 (40.0%)

0 (0.0%)

0.004

Hospital mortality, n (%)

3 (33.3%)

0 (0%)

0.001

1 (20.0%)

0. (0.0%)

0.068

  1. aAKI, acute kidney injury; CKD, chronic kidney disease; CABG, coronary artery bypass graft; LOS, length of stay; RRT, renal replacement therapy. AKI is defined as Risk, Injury, Failure, Loss, End-stage renal disease classification of AKI (RIFLE) class R or worse including serum creatinine increase and urine output decrease. Data are medians (25th to 75th percentiles) unless otherwise indicated. bIncluding intraoperative and 48-hour postoperative values.