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Table 2 Interventions and outcomesa

From: Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study

  All patients Excluding patients with preoperative CKD
Variables AKI ( n = 9) No AKI ( n = 91) P value AKI ( n = 5) No AKI ( n = 69) P value
CABG surgery, n (%) 2 (22.2%) 17 (18.7%) 0.68 1 (20.0%) 13 (18.8%) >0.99
Valve surgery, n (%) 4 (44.5%) 46 (50.5%) >0.99 2 (40.0%) 37 (53.6%) 0.66
CABG and valve surgery, n (%) 3 (33.3%) 21 (23.1%) 0.68 2 (40.0%) 14 (20.3%) 0.29
Thoracic aortic surgery, n (%) 0 (0.0%) 7 (7.7%) >0.99 0 (0.0%) 5 (7.3%) >0.99
Previous cardiothoracic operation, n (%) 2 (22.2%) 26 (28.6%) >0.99 1 (20.0%) 23 (33.3%) >0.99
Duration of bypass, minutes 125 (100 to 172) 119 (91 to 158) 0.62 109 (80 to 146) 119 (90 to 156) 0.57
Fluid balanceb, mL 4,980 (3,000 to 16,200) 3,100 (1,690 to 4,660) 0.035 4,920 (450 to 16,200) 3,100 (1,260 to 4,800) 0.4
Furosemideb, n (%) 9 (100%) 84 (92.3%) 0.39 5 (100.0%) 63 (91.3%) >0.99
Furosemideb, mg 130 (60 to 460) 50 (20 to 90) 0.003 160 (35 to 672) 45 (20 to 70) 0.05
Vasopressor useb, n (%) 7 (77.8%) 65 (71.4%) 0.69 5 (100.0%) 49 (71.0%) 0.32
Inotrope useb, n (%) 8 (88.9%) 51 (63.7%) 0.13 4 (80.0%) 45 (65.2%) 0.66
Blood transfusionb, n (%) 8 (88.9%) 52 (57.1%) 0.06 4 (80.0%) 39 (56.5%) 0.39
Blood transfusionb, mL 1,000 (500 to 6,380) 500 (0 to 500) 0.005 1,250 (250 to 6,800) 250 (0 to 500) 0.048
LOS in hospital, days 14 (8 to 19) 9 (7 to 14) 0.024 14 (8 to 19) 9 (7 to 14) 0.48
Need for RRT, n (%) 3 (33.3%) 2 (2.2%) 0.005 2 (40.0%) 0 (0.0%) 0.004
Hospital mortality, n (%) 3 (33.3%) 0 (0%) 0.001 1 (20.0%) 0. (0.0%) 0.068
  1. aAKI, acute kidney injury; CKD, chronic kidney disease; CABG, coronary artery bypass graft; LOS, length of stay; RRT, renal replacement therapy. AKI is defined as Risk, Injury, Failure, Loss, End-stage renal disease classification of AKI (RIFLE) class R or worse including serum creatinine increase and urine output decrease. Data are medians (25th to 75th percentiles) unless otherwise indicated. bIncluding intraoperative and 48-hour postoperative values.