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Table 2 Monitoring during PEEP changes in ARDS patients included in the studya

From: Lung sonography and recruitment in patients with early acute respiratory distress syndrome: A pilot study

Measurement PEEP 5 cm H2O (N= 10) PEEP 10 cm H2O (N= 10) PEEP 15 cm H2O (N= 10) P value
Arterial blood gas measurements
   PaO2, mmHg 74 ± 15b 90 ± 19c 102 ± 26d <0.001
   PaCO2, mmHg 51 ± 11 50 ± 10 52 ± 12 NS (0.08)
   pH 7.31 ± 0.09 7.32 ± 0.09c 7.3 ± 0.09d 0.002
   SaO2, % 94 ± 3e 97 ± 3 97 ± 3f <0.001
   PaO2/FiO2 106 ± 35e 133 ± 43c 153 ± 57f <0.001
Haemodynamic and ventilatory parameters
   SAP, mmHg 126 ± 18 120 ± 15 122 ± 19 NS (0.39)
   DAP, mmHg 51 ± 11 50 ± 7 53 ± 10 NS (0.4)
   MAP, mmHg 76 ± 10 74 ± 7 75 ± 11 NS (0.6)
   HR, beats/minute 85 ± 14 83 ± 14 85 ± 14 NS (0.6)
   PIP, cmH2O 34 ± 6 37 ± 10c 43 ± 12 NS (0.06)
   MIP, cmH2O 12 ± 2e 18 ± 2c 22 ± 3g <0.001
Lung sonographic evaluation
   Nonaerated lung area, cm2 27 ± 31e 20 ± 24c 11 ± 12f 0.008
  1. aAll data are means ± SD. PEEP, positive end-expiratory pressure; PaO2, arterial oxygen partial pressure; FiO2, fraction of inspired oxygen; PaCO2, carbon dioxide partial pressure; SaO2, oxygen saturation; SAP, systolic arterial pressure; DAP, diastolic arterial pressure; MAP, mean arterial pressure; HR, heart rate; PIP, peak inspiratory pressure; MIP, mean inspiratory pressure. bP < 0.01 comparing PEEP 5 and 10 cm H2O for PaO2 measurements. cP < 0.05 comparing PEEP 10 and 15 cm H2O for PaO2, pH, PaO2/FiO2, PIP, MIP and nonaerated lung area measurements. dP < 0.01 comparing PEEP 5 and 15 cm H2O for PaO2 and pH measurements. eP < 0.05 comparing PEEP 5 and 10 cm H2O for SaO2, PaO2/FiO2, MIP and nonaerated lung area measurements. fP < 0.05 comparing PEEP 5 and 15 cm H2O for SaO2, PaO2/FiO2 and nonaerated lung area measurements. gP < 0.001 comparing PEEP 5 and 15 cm H2O for MIP measurements.