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Figure 7 | Critical Care

Figure 7

From: Mild-stretch mechanical ventilation upregulates toll-like receptor 2 and sensitizes the lung to bacterial lipopeptide

Figure 7

IL-8 expression following instillation of Pam 3 CSK 4 in rabbits submitted previously, or not, to mechanical ventilation. IL-8 mRNA levels were normalized with the expression of GAPDH mRNA. Values are reported as the fold increase compared with control spontaneously breathing (SB) animals normalized to 1 (n = 4 per group). Results are expressed as the mean ± standard deviation. Lung response to bacterial lipopeptide (BLP) was markedly enhanced by previous mechanical ventilation (MV). *P < 0.05 between SB and MV stimulated rabbits.

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