Table 4 Changes in respiratory mechanics, blood gas analysis and VDalv in PaCO2 responders (n = 7) and PaCO2 nonresponders (n = 6)a
Supine | PP H3 | PP H6 | PP H9 | PP H12 | PP H15 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameters | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | P values | |
PaCO2, mmHg) | R | 58 | (55 to 59) | 57 | (51 to 57) | 54 | (44 to 57) | 50 | (46 to 53) | 50 | (46 to 55) | 50 | (47 to 52) | 0.005 |
NR | 56 | (49 to 60) | 52 | (49 to 60) | 54 | (49 to 62) | 54 | (49 to 60) | 56 | (51 to 62) | 57 | (49 to 59) | ||
VDalv/VT | R | 0.40 | (0.37 to 0.45) | 0.31 | (0.29 to 0.46) | 0.23 | (0.31 to 0.40) | 0.26 | (0.26 to 0.42) | 0.28 | (0.24 to 0.44) | 0.28 | (0.23 to 0.43) | 0.005 |
NR | 0.45 | (0.42 to 0.51) | 0.38 | (0.32 to 0.47) | 0.38 | (0.35 to 0.43) | 0.37 | (0.33 to 0.45) | 0.42 | (0.39 to 0.51) | 0.44 | (0.39 to 0.54) | ||
PaO2/FiO2, mmHg | R | 70 | (59 to 78) | 103 | (96 to 136) | 138 | (83 to 146) | 111 | (91 to 156) | 136 | (95 to 142) | 139 | (103 to 148) | 0.0001 |
NR | 63 | (44 to 76) | 83 | (80 to 89) | 79 | (73 to 88) | 83 | (74 to 88) | 84 | (62 to 87) | 89 | (70 to 97) | ||
Pplat, cmH2O | R | 27 | (24 to 27) | 23 | (22 to 25) | 23 | (20 to 25) | 23 | (22 to 25) | 21 | (21 to 25) | 23 | (21 to 25) | 0.002 |
NR | 28 | (26 to 28) | 26 | (24 to 28) | 26 | (25 to 28) | 26 | (25 to 28) | 26 | (25 to 26) | 26 | (25 to 26) | ||
Crs, mL/cmH2O | R | 28 | (15 to 30) | 30 | (18 to 36) | 34 | (17 to 41) | 32 | (18 to 38) | 32 | (19 to 39) | 31 | (18 to 39) | 0.002 |
NR | 15 | (12 to 20) | 15 | (13 to 24) | 15 | (13 to 23) | 15 | (13 to 23) | 15 | (14 to 22) | 15 | (14 to 22) | ||