Table 3 Changes in respiratory mechanics, blood gas analysis and VDalv in PaO2 responders (n = 7) and PaO2 nonresponders (n = 6)a
Supine | PP H3 | PP H6 | PP H9 | PP H12 | PP H15 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameters | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | Median | 1st to 3rd interquartile range | P value | |
PaO2/FiO2, mmHg | R | 51 | (48 to 69) | 91 | (86 to 112) | 94 | (83 to 142) | 97 | (86 to 126) | 98 | (93 to 142) | 108 | (99 to 142) | 0.0003 |
NR | 77 | (76 to 81) | 91 | (82 to 99) | 79 | (73 to 88) | 84 | (82 to 99) | 84 | (82 to 87) | 89 | (82 to 97) | ||
VDalv/VT | R | 0.43 | (0.41 to 0.47) | 0.35 | (0.31 to 0.46) | 0.35 | (0.29 to 0.41) | 0.38 | (0.23 to 0.42) | 0.40 | (0.31 to 0.40) | 0.41 | (0.32 to 0.45) | 0.31 |
NR | 0.42 | (0.36 to 0.50) | 0.35 | (0.28 to 0.47) | 0.31 | (0.22 to 0.43) | 0.32 | (0.27 to 0.44) | 0.36 | (0.28 to 0.51) | 0.35 | (0.27 to 0.53) | ||
PaCO2, mmHg | R | 58 | (54 to 60) | 52 | (51 to 58) | 51 | (47 to 57) | 49 | (48 to 53) | 54 | (48 to 55) | 51 | (47 to 55) | 0.14 |
NR | 55 | (52 to 60) | 56 | (51 to 62) | 57 | (48 to 62) | 55 | (48 to 60) | 54 | (48 to 63) | 53 | (48 to 58) | ||
Pplat, cmH2O | R | 27 | (27 to 30) | 25 | (22 to 26) | 24 | (23 to 26) | 24 | (23 to 26) | 24 | (22 to 26) | 24 | (24 to 25) | 0.27 |
NR | 27 | (24 to 28) | 25 | (24 to 28) | 25 | (22 to 26) | 25 | (23 to 27) | 26 | (22 to 26) | 26 | (25 to 26) | ||
Crs, mL/cmH2O | R | 16 | (13 to 28) | 19 | (16 to 37) | 18 | (16 to 38) | 18 | (16 to 35) | 20 | (17 to 35) | 19 | (17 to 33) | 0.023 |
NR | 19 | (14 to 31) | 21 | (14 to 33) | 21 | (14 to 36) | 21 | (14 to 34) | 19 | (15 to 34) | 19 | (15 to 34) | ||