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Table 5 Multivariate analysis

From: Mild hypoglycemia is independently associated with increased mortality in the critically ill

 

Minimum BG < 40 mg/dL

Minimum BG 40 to 69 mg/dL

Minimum BG < 70 mg/dL

 

OR (95% CI)

P -value

OR (95% CI)

P -value

OR (95% CI)

P -value

Entire cohort 1

( n = 6,240)

1.49 (1.14 to 1.94)

0.0031

1.17 (0.99 to 1.38)

0.0557

1.47 (1.22 to 1.78)

< 0.0001

No diabetes 2

( n = 3,326)

2.42 (1.42 to 4.10)

0.0011

1.33 (1.02 to 1.75)

0.0370

1.65 (1.24 to 2.19)

0.0005

Diabetes 2

( n = 850)

2.37 (1.12 to 5.01)

0.0236

1.58 (0.99 to 2.52)

0.0549

2.48 (1.48 to 4.15)

0.0005

Medical admission 1

( n = 3,441)

1.44 (1.02 to 2.03)

0.0395

1.06 (0.85 to 1.32)

0.6165

1.28 (1.00 to 1.63)

0.0472

Surgical/trauma admission 1 ( n = 2,787)

1.59 (1.05 to 2.40)

0.0283

1.34 (1.04 to 1.72)

0.0220

1.77 (1.34 to 2.34)

< 0.0001

  1. Multivariate model includes age; modified APACHE II score (age component deleted); CV; ICU LOS; mean BG; medical vs. surgical/trauma admission; mechanical ventilation (as indicated)
  2. 1 Does not include mechanical ventilation in the model
  3. 2 Excludes NL patients (for whom MV and diabetes data not available); includes MV in the model
  4. APACHE II, Acute Physiology and Chronic Health Evaluation II disease classification system; BG, blood glucose; CV, coefficient of variation; LOS, length of stay; NL, Netherlands cohort; OR, odds ratio