Skip to main content

Table 5 Multivariate analysis

From: Mild hypoglycemia is independently associated with increased mortality in the critically ill

  Minimum BG < 40 mg/dL Minimum BG 40 to 69 mg/dL Minimum BG < 70 mg/dL
  OR (95% CI) P -value OR (95% CI) P -value OR (95% CI) P -value
Entire cohort 1
( n = 6,240)
1.49 (1.14 to 1.94) 0.0031 1.17 (0.99 to 1.38) 0.0557 1.47 (1.22 to 1.78) < 0.0001
No diabetes 2
( n = 3,326)
2.42 (1.42 to 4.10) 0.0011 1.33 (1.02 to 1.75) 0.0370 1.65 (1.24 to 2.19) 0.0005
Diabetes 2
( n = 850)
2.37 (1.12 to 5.01) 0.0236 1.58 (0.99 to 2.52) 0.0549 2.48 (1.48 to 4.15) 0.0005
Medical admission 1
( n = 3,441)
1.44 (1.02 to 2.03) 0.0395 1.06 (0.85 to 1.32) 0.6165 1.28 (1.00 to 1.63) 0.0472
Surgical/trauma admission 1 ( n = 2,787) 1.59 (1.05 to 2.40) 0.0283 1.34 (1.04 to 1.72) 0.0220 1.77 (1.34 to 2.34) < 0.0001
  1. Multivariate model includes age; modified APACHE II score (age component deleted); CV; ICU LOS; mean BG; medical vs. surgical/trauma admission; mechanical ventilation (as indicated)
  2. 1 Does not include mechanical ventilation in the model
  3. 2 Excludes NL patients (for whom MV and diabetes data not available); includes MV in the model
  4. APACHE II, Acute Physiology and Chronic Health Evaluation II disease classification system; BG, blood glucose; CV, coefficient of variation; LOS, length of stay; NL, Netherlands cohort; OR, odds ratio