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Table 2 Characteristics of patients with hypoglycemia and patients without hypoglycemia

From: Mild hypoglycemia is independently associated with increased mortality in the critically ill

  ALL ST NL GL
  HYPO NON HYPO NON HYPO NON HYPO NON
Demographics and outcomes         
Number 2,309 3,921 857 2,406 1,084 979 372 542
Age (years) 70 (57 to 79) 66 (52 to 71) 75 (60 to 83) 66 (51 to 78) 69 (58 to 78) 68 (55 to 78) 66 (51 to 75) 65 (52 to 73)
DM (%) 27.3 17.5 29.6 17.2 N/A N/A 22.5 18.7
Diagnostic Category (%)         
Medical 64.5 49.8 69.7 48.5 65.5 61.7 48.7 33.4
Surgical/Trauma 35.5 50.2 30.3 51.5 34.5 38.3 51.3 66.6
Mechanical ventilation 63.3 38.5 55.0 28.5 N/A N/A 82.6 83.5
ICU Length of Stay 5.0 (2.2 to 10.5) 1.8 (1.0 to 3.3) 3.0 (1.4 to 7.1) 1.2 (0.8 to 2.3) 5.2 (2.6 to 10.3) 2.0 (1.3 to 3.2) 9 (5 to 17) 5 (3 to 9)
APACHE II score 20 (14 to 26) 14 (10 to 19) 21.1 (9.3) 14.2 (8.1) 21.2 (7.8) 17.8 (8.4) 18.7 (7.5) 15.3 (6.5)
Mortality (%) 29.6 13.1 29.1 8.91 30.1 23.2 29.6 14.0
Glucose control parameters         
Number of BG measurements per patient 45 (21 to 97) 11 (7 to 24) 35 (16 to 90) 11 (7 to 23) 47 (24 to 92) 9 (5 to 18) 69 (29 to 136) 20 (10 to 48)
Number of BG measurements per day* 9.5 (7.2 to 11.9) 8.0 (5.0 to 10.0) 11.7 9.2 9.0 4.5 7.7 4.0
Mean (mg/dL)^ 118.3 (108.1 to 132.5) 128.1 (115.3 to 144.4) 120.3 (108.4 to 133.9) 125.4 (113.4 to 138.6)1 116.9 (107.5 to 129.9) 131.9 (119.2 to 152.6) 119.1 (109.0 to 136.3) 137.5 (121.0 to 158.4)
CV (%) 31.6 (25.0 to 40.0) 19.2 (13.7 to 26.1) 29.3 (23.1 to 38.2) 18.4 (13.0 to 24.6) 34.2 (23.0 to 42.4) 21.7 (15.0 to 30.2) 27.7 (22.6 to 35.5) 20.2 (15.2 to 25.8)
SD (mg/dL) 24.8 (16.7 to 36.0) 37.6 (28.9 to 50.4) 34.9 (26.2 to 48.8) 22.7 (15.4 to 32.5) 40.2 (31.2 to 54.1) 28.1 (18.8 to 44.5) 34.8 (25.7 to 46.6) 27.5 (19.1 to 38.8)
  1. *Calculated as (mean number of BG tests/mean ICU LOS)
  2. ^These values represent the median (IQR) of the individual patients' mean BG
  3. Data expressed as median (interquartile range), or percentages
  4. APACHE II, Acute Physiology and Chronic Health Evaluation II disease classification system; BG, blood glucose; CV, coefficient of variation; DM, diabetes mellitus; GL, GLUCONTROL cohort; HYPO, hypoglycemia (BG < 70 mg/dL); LOS, length of stay (days); NL, Netherlands cohort; NON, no hypoglycemia; SD, standard deviation; ST, Stamford cohort.