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Table 2 Characteristics of patients with hypoglycemia and patients without hypoglycemia

From: Mild hypoglycemia is independently associated with increased mortality in the critically ill

 

ALL

ST

NL

GL

 

HYPO

NON

HYPO

NON

HYPO

NON

HYPO

NON

Demographics and outcomes

        

Number

2,309

3,921

857

2,406

1,084

979

372

542

Age (years)

70 (57 to 79)

66 (52 to 71)

75 (60 to 83)

66 (51 to 78)

69 (58 to 78)

68 (55 to 78)

66 (51 to 75)

65 (52 to 73)

DM (%)

27.3

17.5

29.6

17.2

N/A

N/A

22.5

18.7

Diagnostic Category (%)

        

Medical

64.5

49.8

69.7

48.5

65.5

61.7

48.7

33.4

Surgical/Trauma

35.5

50.2

30.3

51.5

34.5

38.3

51.3

66.6

Mechanical ventilation

63.3

38.5

55.0

28.5

N/A

N/A

82.6

83.5

ICU Length of Stay

5.0 (2.2 to 10.5)

1.8 (1.0 to 3.3)

3.0 (1.4 to 7.1)

1.2 (0.8 to 2.3)

5.2 (2.6 to 10.3)

2.0 (1.3 to 3.2)

9 (5 to 17)

5 (3 to 9)

APACHE II score

20 (14 to 26)

14 (10 to 19)

21.1 (9.3)

14.2 (8.1)

21.2 (7.8)

17.8 (8.4)

18.7 (7.5)

15.3 (6.5)

Mortality (%)

29.6

13.1

29.1

8.91

30.1

23.2

29.6

14.0

Glucose control parameters

        

Number of BG measurements per patient

45 (21 to 97)

11 (7 to 24)

35 (16 to 90)

11 (7 to 23)

47 (24 to 92)

9 (5 to 18)

69 (29 to 136)

20 (10 to 48)

Number of BG measurements per day*

9.5 (7.2 to 11.9)

8.0 (5.0 to 10.0)

11.7

9.2

9.0

4.5

7.7

4.0

Mean (mg/dL)^

118.3 (108.1 to 132.5)

128.1 (115.3 to 144.4)

120.3 (108.4 to 133.9)

125.4 (113.4 to 138.6)1

116.9 (107.5 to 129.9)

131.9 (119.2 to 152.6)

119.1 (109.0 to 136.3)

137.5 (121.0 to 158.4)

CV (%)

31.6 (25.0 to 40.0)

19.2 (13.7 to 26.1)

29.3 (23.1 to 38.2)

18.4 (13.0 to 24.6)

34.2 (23.0 to 42.4)

21.7 (15.0 to 30.2)

27.7 (22.6 to 35.5)

20.2 (15.2 to 25.8)

SD (mg/dL)

24.8 (16.7 to 36.0)

37.6 (28.9 to 50.4)

34.9 (26.2 to 48.8)

22.7 (15.4 to 32.5)

40.2 (31.2 to 54.1)

28.1 (18.8 to 44.5)

34.8 (25.7 to 46.6)

27.5 (19.1 to 38.8)

  1. *Calculated as (mean number of BG tests/mean ICU LOS)
  2. ^These values represent the median (IQR) of the individual patients' mean BG
  3. Data expressed as median (interquartile range), or percentages
  4. APACHE II, Acute Physiology and Chronic Health Evaluation II disease classification system; BG, blood glucose; CV, coefficient of variation; DM, diabetes mellitus; GL, GLUCONTROL cohort; HYPO, hypoglycemia (BG < 70 mg/dL); LOS, length of stay (days); NL, Netherlands cohort; NON, no hypoglycemia; SD, standard deviation; ST, Stamford cohort.