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Table 5 Relation between length of longest episode of oliguria during an ICU day at risk (patient day without a diagnosis of RIFLE I[Cr]) and AKI-Cr in the next day considering only data gathered during the first three days of ICU admission

From: Oliguria as predictive biomarker of acute kidney injury in critically ill patients

Longest duration of oliguria Days with AKI-Cr next day Days with no AKI-Cr next day Sens. Spec. PPV NPV LR P RR of AKI-Cr
None 5 238        
≥1 hr 18 175 0.78 0.57 0.09 0.98 1.9 < 0.001 4.5
≥2 hr 15 130 0.68 0.69 0.10 0.98 2.2 < 0.001 4.3
≥3 hr 13 91 0.56 0.78 0.13 0.97 2.6 < 0.001 4.2
≥4 hr 12 71 0.52 0.83 0.14 0.97 3.0 < 0.001 4.6
≥5 hr 7 59 0.30 0.85 0.11 0.96 2.1 0.06 2.5
≥6 hr 5 40 0.22 0.90 0.11 0.95 2.2 0.08 2.4
≥12 hr 4 8 0.17 0.98 0.33 0.96 9.0 0.002 7.4
  1. Receiver-operator characteristic area under the curve for this comparison = 0.72 (0.61-0.83). P-values refer to Fisher's exact test for presence or absence of stated degree of oliguria and AKI outcome.
  2. AKI-Cr, acute kidney injury defined by changes in serum creatinine; LR, likelihood ratio (positive); NPV, negative predictive value; PPV, positive predictive value; Sens, sensitivity; Spec, specificity; RR, relative risk.