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Table 2 Hemodynamic parameters of patients treated with levosimendan

From: Levosimendan inhibits release of reactive oxygen species in polymorphonuclear leukocytes in vitro and in patients with acute heart failure and septic shock: a prospective observational study

A) Acute heart failure (n = 16)

   

Hemodynamic parameters

before levosimendan

after levosimendan

P value

EF (%)

24 (20-29)

38 (29-59)

0.003

MAP (mmHg)

80 (70-90)

75 (70-80)

ns

CVP (mmHg)

8 (6-15)

9 (5-14)

ns

CI (l/min/m2)

2.5 (2.3-2.6)

2.7 (2.6-3.3)

0.04

B) Septic cardiac failure (n = 9)

   

Hemodynamic parameters

before levosimendan

after levosimendan

P value

EF (%)

29 (21-30)

30 (22-38)

ns

MAP (mmHg)

75 (73-80)

75 (75-85)

ns

CVP (mmHg)

9 (5-13)

12 (9-14)

ns

CI (l/min/m2)

2.2 (1.9-3.0)

3.2 (2.4-3.9)

ns

  1. Table shows hemodynamic parameters of (a) patients with acute heart failure (n = 16) and (b) patients with septic cardiac failure (n = 9) before levosimendan treatment and after levosimendan treatment (after 24 hours). Data are expressed as median (interquartile range).
  2. CI, cardiac index; CVP, central venous pressure; EF, ejection fraction; MAP, mean arterial pressure; ns, not significant.
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