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Table 3 Multivariable analysis of association between inotrope exposure and hospital mortalitya

From: The relationship between inotrope exposure, six-hour postoperative physiological variables, hospital mortality and renal dysfunction in patients undergoing cardiac surgery

Variable

Crude odds ratio

Adjusted odds ratio (95% CI)

Pvalue

Inotrope status

   

   Inotrope unexposed (ref)

1.0

1.0

 

   Inotrope exposed

9.1

2.3 (1.2 to 4.5)

0.01

Parsonnet score

   

   0 to 9 (ref)

1.0

1.0

 

   10 to 14

2.4

1.8 (0.7 to 4.6)

0.24

   15 to 19

3.1

1.8 (0.7 to 4.9)

0.23

   20 to 29

8.3

4.6 (2.0 to 10.9)

< 0.001

   ≥ 30

24.6

11.2 (4.6 to 27.5)

< 0.001

Ejection fraction

   

   LVEF ≥ 30%

1.0

  

   LVEF < 30%

2.2

1.5 (0.9 to 2.7)

0.15

Intraaortic balloon pump use

   

   No perioperative IABP use

1.0

  

   Perioperative IABP use

8.2

3.3 (1.9 to 5.8)

< 0.001

Bypass timeb

1.6

1.3 (1.1 to 1.4)

< 0.001

Reoperative status

   

   No reoperation

1.0

  

   Reoperation

6.1

4.7 (2.3 to 9.3)

< 0.001

Cardiac index at six hours, L/min

   

   Cardiac index ≥ 2.2 (ref)

1.0

1.0

 

   Cardiac index < 2.2

2.8

1.7 (0.93 to 1)

0.09

  1. aLVEF, left ventricular ejection fraction; IABP, intraaortic balloon pump; ref, reference value; CI, confidence interval; bmodelled linearly as an increase in bypass time of 30 minutes.