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Table 3 Evidence for loop diuretic therapy in acute tubular necrosis (ATN)

From: Systematic review: The use of diuretics and dopamine in acute renal failure: a systematic review of the evidence

Indication (result)

Strength of

Source

 

evidence

 

Radiocontrast ATN

  

   For prevention (no)

Level I

Solomon et al [3]

Ischemic ATN

  

   For prevention (?)

No data in humans

 

   Vascular surgery (no)

Level I*

Hager et al [8]

Treatment of ATN

  

   Rhabdomyolysis (no)

Level IV

Better et al [7]

Improves outcome (no)

Level II

Kleinknecht et al [11]

  1. *Loop diuretics were begun after surgery and continued through the ICU stay.
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Critical Care

ISSN: 1364-8535