Table 2 Comparison of the characteristics of patients receiving either nicardipine or labetalol
Characteristic n (%), unless otherwise indicated | Nicardipine (n= 110) | Labetalol (n= 116) |
|---|---|---|
Mean age, years ± SD | 53.3 ± 15.3 | 51.9 ± 13.9 |
Female | 60 (54.6) | 59 (50.9) |
White | 28 (25.5) | 24 (20.9) |
African American | 82 (74.6) | 90 (78.3) |
Smoking history | 54 (49.1) | 78 (67.2) |
Current smoker | 30 (27.3) | 49 (42.2) |
Stimulant use history (cocaine or amphetamines) | 17 (15.5) | 23 (19.8) |
Median basal metabolic index (IQR) | 29.3 (24.5, 34.3) | 29.4 (25.1, 34.0) |
Median heart rate, bpm (IQR) | 85 (76, 98) | 85 (73, 97) |
Chest pain | 33(30.0) | 26 (22.4) |
Diminished consciousness | 1 (0.9) | 5 (4.3) |
Headache | 48 (43.6) | 58 (50.0) |
Shortness of breath | 34 (30.9) | 27 (23.3) |
Past medical history | ||
Hypertension | 105 (96.3) | 109 (94.0) |
Hypertension crisis hospitalization | 40 (38.8) | 39 (36.4) |
Hyperlipidemia | 46 (43.4) | 31 (27.9) |
Diabetes | 38 (34.6) | 25 (21.7) |
Coronary artery disease | 17 (15.7) | 15 (13.0) |
Dialysis | 16 (14.6) | 12 (10.5) |
Stroke | 10 (9.2) | 7 (6.2) |
Heart failure | 8 (7.3) | 12 (10.6) |
Myocardial infarction | 7 (6.5) | 7 (6.03) |
Baseline laboratory/ECG | ||
Median creatinine, mg/dL (IQR) | 1.2 (0.9, 3.0) | 1.1 (0.9, 1.8) |
Median BNP, pg/dL (IQR) | 365.5 (117, 1981) | 183.5 (125, 1825) |
Median troponin I (ng/mL) | 0.0 (0.0, 0.2) | 0.0 (0.0, 0.1) |
Abnormal electrocardiogram | 25 (27.2) | 28 (28.9) |