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Table 2 Distribution of infections, infection characteristics, and pathogens for main and sepsis population

From: Gender-related outcome difference is related to course of sepsis on mixed ICUs: a prospective, observational clinical study

 

Main population

Sepsis population

 

Number

400

309

197

130

Patients with infections n (%)

248 (62.0%)a

164 (53.1%)a

197 (100%)

130 (100%)

   Colitis, pseudomembranous

2 (0.5%)

3 (1.0%)

2 (1.0%)

2 (1.5%)

   Pneumonia

135 (33.8%)a

75 (24.3%)a

124 (62.9%)

70 (53.8%)

   Lower urinary tract infections

13 (3.3%)a

34 (11.0%)a

11 (5.6%)a

30 (23.1%)a

   Bones and joints

11 (2.8%)

7 (2.3%)

8 (4.1%)

6 (4.6%)

   Endocarditis

11 (2.8%)

7 (2.3%)

10 (5.1%)

6 (4.6%)

   Abdomen

40 (10.0%)

28 (9.1%)

32 (16.2%)

18 (13.8%)

   Soft tissue and wounds

80 (20.0%)

47 (15.2%)

55 (27.9%)

38 (29.2%)

   Upper urinary tract infections

6 (1.5%)

4 (1.3%)

3 (1.5%)

1 (0.8%)

   Meningitis

5 (1.3%)

5 (1.6%)

4 (2.0%)

3 (2.3%)

   Bloodstream infection

35 (8.8%)

17 (5.5)%)

34 (17.3%)

16 (12.3%)

   Fever of unknown origin

33 (8.3%)

24 (7.8%)

22 (11.2%)

17 (13.1%)

   Catheter-related infections

17 (4.3%)

5 (1.6%)

17 (8.6%)

5 (3.8%)

SIRS occurrence n (%)

364 (91.0%)

290 (93.9%)

197 (100%)

130 (100%)

Sepsis occurrence n (%)

197 (49.3%)

130 (42.1%)

197 (100%)

130 (100%)

Severe sepsis occurrence n (%)

89 (22.3%)a

48 (15.5%)a

89 (45.2%)

48 (36.9%)

Septic shock occurrence n (%)

74 (18,5%)

41 (13,3%)

74 (37.6%)

41 (31.5%)

Fungi detected

64 (16.0%)

47 (15.2%)

61 (31.0%)

42 (32.3%)

Gram-negative germs detected

98 (24.5%)

58 (18.8%)

89 (45.2%)

52 (40.0%)

Difficult-to-treat bacteria detected

41 (10.3%)

28 (9.1%)

37 (18.8%)

26 (20.0%)

  1. aP < 0.05 in a two-tailed χ2 test. More than one infection period per patient was possible. Difficult-to-treat pathogens include bacteria associated with potential intrinsic or acquired resistance (methicillin-resistant Staphylococcus aureus, germs producing extended spectrum betalactamases, Vancomycin-resistant Enterococci, nonfermenters like Pseudomonas spp., Stenotrophomonas maltophilia, Acinetobacter baumanii, Citrobacter spp., Enterobacter cloacae, Enterococcus faecium, and Bacillus cereus). Binary parameters presented in total and percentage (%). SIRS, systemic inflammatory response syndrome.