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Table 2 Distribution of infections, infection characteristics, and pathogens for main and sepsis population

From: Gender-related outcome difference is related to course of sepsis on mixed ICUs: a prospective, observational clinical study

  Main population Sepsis population
 
Number 400 309 197 130
Patients with infections n (%) 248 (62.0%)a 164 (53.1%)a 197 (100%) 130 (100%)
   Colitis, pseudomembranous 2 (0.5%) 3 (1.0%) 2 (1.0%) 2 (1.5%)
   Pneumonia 135 (33.8%)a 75 (24.3%)a 124 (62.9%) 70 (53.8%)
   Lower urinary tract infections 13 (3.3%)a 34 (11.0%)a 11 (5.6%)a 30 (23.1%)a
   Bones and joints 11 (2.8%) 7 (2.3%) 8 (4.1%) 6 (4.6%)
   Endocarditis 11 (2.8%) 7 (2.3%) 10 (5.1%) 6 (4.6%)
   Abdomen 40 (10.0%) 28 (9.1%) 32 (16.2%) 18 (13.8%)
   Soft tissue and wounds 80 (20.0%) 47 (15.2%) 55 (27.9%) 38 (29.2%)
   Upper urinary tract infections 6 (1.5%) 4 (1.3%) 3 (1.5%) 1 (0.8%)
   Meningitis 5 (1.3%) 5 (1.6%) 4 (2.0%) 3 (2.3%)
   Bloodstream infection 35 (8.8%) 17 (5.5)%) 34 (17.3%) 16 (12.3%)
   Fever of unknown origin 33 (8.3%) 24 (7.8%) 22 (11.2%) 17 (13.1%)
   Catheter-related infections 17 (4.3%) 5 (1.6%) 17 (8.6%) 5 (3.8%)
SIRS occurrence n (%) 364 (91.0%) 290 (93.9%) 197 (100%) 130 (100%)
Sepsis occurrence n (%) 197 (49.3%) 130 (42.1%) 197 (100%) 130 (100%)
Severe sepsis occurrence n (%) 89 (22.3%)a 48 (15.5%)a 89 (45.2%) 48 (36.9%)
Septic shock occurrence n (%) 74 (18,5%) 41 (13,3%) 74 (37.6%) 41 (31.5%)
Fungi detected 64 (16.0%) 47 (15.2%) 61 (31.0%) 42 (32.3%)
Gram-negative germs detected 98 (24.5%) 58 (18.8%) 89 (45.2%) 52 (40.0%)
Difficult-to-treat bacteria detected 41 (10.3%) 28 (9.1%) 37 (18.8%) 26 (20.0%)
  1. aP < 0.05 in a two-tailed χ2 test. More than one infection period per patient was possible. Difficult-to-treat pathogens include bacteria associated with potential intrinsic or acquired resistance (methicillin-resistant Staphylococcus aureus, germs producing extended spectrum betalactamases, Vancomycin-resistant Enterococci, nonfermenters like Pseudomonas spp., Stenotrophomonas maltophilia, Acinetobacter baumanii, Citrobacter spp., Enterobacter cloacae, Enterococcus faecium, and Bacillus cereus). Binary parameters presented in total and percentage (%). SIRS, systemic inflammatory response syndrome.