Table 1 Distribution of basic characteristics between gender in the main population and in the sepsis subgroup

♂

♀

♂

♀

n = 400

n = 309

n = 197

n = 130

Age (years)

66 (51|72)^a

68 (54|78)^a

64 (50|72)^a

68 (57|78)^a

Drug abuse

18 (4.5%)^a

3 (1.0%)^a

14 (7.1)^a

1 (0.8)^a

Nicotine abuse

56 (14.0%)^a

15 (4.9%)^a

25 (12.7)

9 (6.9)

Alcohol abuse

55 (13.8%)^a

10 (3.2%)^a

33 (16.8)^a

8 (6.2)^a

Preexisting comorbidity

   Immunosuppressive status

27 (6.8%)

31 (10.0%)

11 (5.6%)^a

18 (13.8%)^a

   Vascular disease

202 (50.5%)^a

111 (35.9%)^a

100 (50.8%)^a

45 (34.6%)^a

   Hypertension

178 (44.5%)

147 (47.6%)

82 (41.6%)

60 (46.2%)

   Chronic liver disease

32 (8.0%)

16 (5.2%)

17 (8.6%)

8 (6.2%)

   Chronic renal disease

67 (16.8%)

46 (14.9%)

37 (18.8%)

24 (18.5%)

   Metabolic disease

172 (43.0%)

141 (45.6%)

102 (51.8%)

71 (54.6%)

   Chronic lung disease

45 (11.3%)

37 (12.0%)

27 (13.7%)

20 (15.4%)

   Psychiatric disease

81 (20.3%)

47 (15.2%)

53 (26.9%)

31 (23.8%)

Admission category

   Infection

14 (3.5%)

10 (3.2%)

10 (5.1%)

7 (5.4%)

   Malignant tumor

65 (16.3%)

80 (25.9%)

27 (13.7%)

21 (16.2%)

   Neurology

43 (10.8%)

34 (11.0%)

23 (11.7%)

20 (15.4%)

   Cardiovascular

154 (38.5%)

90 (29.1%)

67 (34.0%)

34 (26.2%)

   Respiratory

21 (5.3%)

17 (5.5%)

15 (7.6%)

16 (12.3%)

   Gastrointestinal

30 (7.5%)

19 (6.1%)

20 (10.2%)

9 (6.9%)

   Trauma

42 (10.5%)

29 (9.4%)

23 (11.7%)

11 (8.5%)

   Others

31 (7.8%)

30 (9.7%)

12 (6.1%)

12 (9.2%)

Surgical patients

327 (81.8%)

262 (84.8%)

151 (76.6%)

100 (76.9%)

OP category of surgical patients

   Neurosurgical

38 (11.6%)

40 (15.3%)

19 (12.6%)

19 (19.0%)

   Musculoskeletal

59 (18.0%)

46 (17.6%)

33 (21.9%)

19 (19.0%)

   Cardiac

134 (41.0%)

65 (24.8%)

52 (34.4%)

20 (20.0%)

   Abdomen and urogenital

83 (25.4%)

97 (37.0%)

41 (27.2%)

30 (30.0%)

   Thorax

9 (2.8%)

9 (3.4%)

4 (2.6%)

7 (7.0%)

   Soft tissue and others

4 (1.2%)

5 (1.9%)

2 (1.3%)

5 (5.0%)

Severity of disease scorings

   SAPS-II on admission

35 (26|47)

34 (26|45)

39 (28|51)

40 (29|53)

   SOFA on admission

5 (2|8)^a

4 (2|7)^a

6 (4|9)^a

5 (3|7)^a

   TISS-28 on admission

35 (26|42)

33 (27|40)

37 (29|44)

35 (28|41)

Diagnostic patterns

Microbiologic diagnostics (% of LOS)

17.0 (± 20.4)

14.9 (± 19.8)

27.6 (± 19.3)

24.3 (± 17.3)

Radiologic diagnostics of (% of LOS)

55.2 (± 30.0)^a

51.1 (± 31.0)^a

52.1 (± 23.0)^a

45.4 (± 21.3)^a

Antibiotic therapy

   SOP adherence (% of LOS)

77.3 (± 32.6)

79.0 (± 33.2)

68.9 (± 34.4)

69.3 (± 36.4)

   DAU in agents per day

1.0 (0.5|1.5)

1.0 (0.5|1.5)

1.26 (± 0.65)

1.18 (± 0.74)

   Antibiotic-free days (% of LOS)

28.8 (± 27.9)

27.3 (± 27.6)

22.0 (± 22.4)

25.4 (± 24.3)

   Daily costs for antibiotics in €

19.3 (± 25.5)

15.6 (± 21.6)

30.7 (± 28.6)

26.7 (± 27.1)

   Duration of treatment

   ICU stay in days

4 (2|11)

4 (2|9.5)

10 (5|19)

10 (5|20)

   Invasive ventilation in hours^b

27 (11|121)^a

20 (8|95)^a

96 (22|305)

85 (16|300)