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Figure 2 | Critical Care

Figure 2

From: Short term Candida albicans colonization reduces Pseudomonas aeruginosa-related lung injury and bacterial burden in a murine model

Figure 2

Effect of previous C. albicans tracheobronchial colonization on P. aeruginosa -related lung injury. A. BALB/c mice survival. Effect of C. albicans (Ca), P. aeruginosa (Pa), and P. aeruginosa after C. albicans (CaPa) on mouse survival during four days after intratracheal instillation of a dose of 1 × 105 CFU/mouse of C. albicans at T0 and of 1 × 107 CFU/mouse for P. aeruginosa administrated at Day 2 post-colonization. n = 8 mice per group. B. Effect of C. albicans and P. aeruginosa on alveolar-capillary barrier permeability. Evaluation of endothelial permeability (EP) of the alveolar-capillary barrier to 125I-labeled bovine serum albumin four days after the intratracheal instillation of a saline solution (Ctr) and in Ca, Pa, CaPa groups. The data are means ± SE (indicated by error bars). n = 8 mice per group.

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