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Table 2 AUC ROC results comparing diagnostic performance between control and various clinical cohorts

From: Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis

Comparison

Biomarker Set

Mean

SD‡

P-value*

MI Vs HC

42

0.921

0.0568

< 0.002

MI Vs HC

7

0.862

0.0640

< 0.002

Sepsis Vs HC

42

0.938

0.0557

< 0.002

Sepsis Vs HC

7

0.910

0.0479

< 0.002

PS Vs HC

42

0.891

0.0687

< 0.002

PS Vs HC

7

0.833

0.0661

< 0.002

Sepsis Vs PS

42

0.921

0.0568

< 0.002

Sepsis Vs PS

7

0.862

0.0640

< 0.002

  1. ‡ Standard Deviation; *Statistical significance is assumed when P < 0.05. Based on 500 random permutations the minimum possible P-value is < 0.002
  2. § HC -- Healthy Control; MI -- Mixed Inflammation; PS-Post Surgical