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Table 3 Hemodynamic support with fluids and vasoactive drugs

From: Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial

 

MICO

n = 199

Control

n = 187

P- value

Volume replacement; mL/kg

   

Total

   

0 to 6 hrs

11.4 (5.0 to 20.9)

9.1 (2.7 to 19.5)

.22

7 to 24 hrs

14.2 (5.6 to 28.2)

13.2 (5.4 to 29.4)

.76

0 to 24 hrs

28.6 (16.3 to 45.8)

24.9 (15.0 to 48.0)

.40

Colloids

   

0 to 6 hrs

5.8 (0.0 to 12.1)

4.9 (0.0 to 9.7)

.33

7 to 24 hrs

6.7(1.9 to 14.8)

5.7 (0.0 to 13.0)

.06

0 to 24 hrs

14.9 (6.7 to 22.1)

11.0 (5.6 to 23.3)

.09

Crystalloids

   

0 to 6 hrs

0.0 (0.0 to 8.0)

0.0 (0.0 to 7.0)

.54

7 to 24 hrs

0.0 (0.0 to 11.0)

0.0 (0.0 to 13.0)

.58

0 to 24 hrs

6.0 (0.0 to 22.0)

6.0 (0.0 to 20.0)

.81

Blood products

   

0 to 6 hrs

0.0 (0.0 to 4.0)

0.0 (0.0 to 3.0)

.76

7 to 24 hrs

0.0 (0.0 to 0.0)

0.0 (0.0 to 0.0)

.62

0 to 24 hrs

0.0 (0.0 to 6.0)

0.0 (0.0 to 7.0)

.64

Any vasoactive drug

150 (75)

150 (80)

.27

dobutamine

44 (22)

45 (24)

.72

noradrenaline

115 (58)

103 (55)

.61

adrenaline

19 (10)

14 (7)

.59

vasodilator

26 (13)

42 (22)

.02

beta-blocking agents

6 (3)

14 (7)

.07

other anti-arrhythmic drugs

14 (7)

23 (12)

.09

  1. Fluids given for basal daily needs of water and electrolytes (maintenance fluids) excluded. Values are median (interquartile range) for fluids and number of patients (percentage) receiving vasoactive drugs.
  2. MICO, minimally invasive cardiac output.
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Critical Care

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