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Table 3 Hemodynamic support with fluids and vasoactive drugs

From: Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial

  MICO
n = 199
Control
n = 187
P- value
Volume replacement; mL/kg    
Total    
0 to 6 hrs 11.4 (5.0 to 20.9) 9.1 (2.7 to 19.5) .22
7 to 24 hrs 14.2 (5.6 to 28.2) 13.2 (5.4 to 29.4) .76
0 to 24 hrs 28.6 (16.3 to 45.8) 24.9 (15.0 to 48.0) .40
Colloids    
0 to 6 hrs 5.8 (0.0 to 12.1) 4.9 (0.0 to 9.7) .33
7 to 24 hrs 6.7(1.9 to 14.8) 5.7 (0.0 to 13.0) .06
0 to 24 hrs 14.9 (6.7 to 22.1) 11.0 (5.6 to 23.3) .09
Crystalloids    
0 to 6 hrs 0.0 (0.0 to 8.0) 0.0 (0.0 to 7.0) .54
7 to 24 hrs 0.0 (0.0 to 11.0) 0.0 (0.0 to 13.0) .58
0 to 24 hrs 6.0 (0.0 to 22.0) 6.0 (0.0 to 20.0) .81
Blood products    
0 to 6 hrs 0.0 (0.0 to 4.0) 0.0 (0.0 to 3.0) .76
7 to 24 hrs 0.0 (0.0 to 0.0) 0.0 (0.0 to 0.0) .62
0 to 24 hrs 0.0 (0.0 to 6.0) 0.0 (0.0 to 7.0) .64
Any vasoactive drug 150 (75) 150 (80) .27
dobutamine 44 (22) 45 (24) .72
noradrenaline 115 (58) 103 (55) .61
adrenaline 19 (10) 14 (7) .59
vasodilator 26 (13) 42 (22) .02
beta-blocking agents 6 (3) 14 (7) .07
other anti-arrhythmic drugs 14 (7) 23 (12) .09
  1. Fluids given for basal daily needs of water and electrolytes (maintenance fluids) excluded. Values are median (interquartile range) for fluids and number of patients (percentage) receiving vasoactive drugs.
  2. MICO, minimally invasive cardiac output.