Skip to main content

Table 2 Characteristics of patients, clinical presentation and outcome of confirmed critical illness related to H1N1 2009 influenza in 2010 and 2009

From: Critical care services and the H1N1 (2009) influenza epidemic in Australia and New Zealand in 2010: the impact of the second winter epidemic

 

2010

2009

P-value

Age, years

   

Median (IQR)

42 (28 to 53)

39.8 (27 to 53)

0.86

Age distribution, years no./total no. (%)

  

0.13

   0 to < 1

8/271 (3%)

34/921 (4%)

0.45

   1 to 4

12/271 (4%)

21/921 (2%)

0.1

   5 to 24

31/271 (11%)

128/921 (14%)

0.21

   25 to 49

128/271 (47%)

415/921 (45%)

0.92

   50 to 64

87/271 (32%)

242/921 (26%)

0.13

   > 65

16/271 (6%)

79/921 (9%)

0.11

Female sex, no./total no. (%)

134/283 (47%)

498/921 (54%)

0.048

Pregnant or post-partum women,

29/283(10.2%)

81/921 (8.8%)

0.54

Ethnicity, no./total no. (%)

   

   Caucasian

212/280 (75.7%)

633/887 (71.4%)

0.16

   Aboriginal or Torres Strait Islander admitted to ICU in Australia

9/199 (4.5%)

82/765 (10.7%)

0.01

   Maori admitted to ICU in New Zealand

16/81 (19.8%)

34/122 (27.9%)

0.25

   Pacific Islander

13/280 (4.6%)

43/887 (4.8%)

0.89

   Asian

13/280 (4.6%)

39/887 (4.4%)

0.86

   Other

17/280 (6%)

56/887 (6.3%)

0.88

Adults with BMI > 35, no./total no. (%)

60/215 (27.9%)

177/642 (27.6%)

0.96

Diabetes, no./total no. (%)

42/277 (15%)

148/900 (16%)

0.61

Asthma or chronic obstructive pulmonary disease, no./total no. (%)

73/278(26%)

297/915 (32.5%)

0.05

Chronic heart failure, no./total no. (%)

14/277 (5%)

99/910 (10.9%)

0.004

APACHE III or pediatric co-morbidity, no./total no. (%)

52/279 (19%)

251/891 (28.2%)

0.002

No known predisposing factors, no./total no. (%)

107/283 (38%)

300/921 (33%)

0.1

Influenza syndrome

  

< 0.001

   Viral pneumonitis or ARDS, no./total no. (%)

147/255 (58%)

438/896 (48.9%)

0.014

   Secondary bacterial pneumonia, no./total no. (%)

71/255 (28%)

177/896 (19.6%)

0.006

   Exacerbation of airflow limitation, no./total no. (%)

20/255 (8%)

120/896 (13.4%)

0.017

   Inter-current illness or other, no./total no. (%)

17/255 (6.7%)

161/896 (18%)

0.001

Duration of treatment in ICU, days

Median (IQR)

8.5 (3.2 to 16.1)

7 (3.0 to 16)

0.32

Duration of treatment in hospital, days

Median (IQR)

15.4 (7.5 to 25.6)

16.6 (7.0 to 31.0)

0.38

Patients treated with MV, no./total no. (%)

186/282 (66%)

579/909 (63.7%)

0.53

Patients treated with vasopressor drugs, no./total no. (%)

104/269 (39%)

276/787 (35%)

0.29

Patients treated with renal replacement therapy, no./total no. (%)

20/275 (7.3%)

50/800 (6.3%)

0.65

Patients treated with ECMO, no./total no. (%)

12/278 (4.3%)

57/579 (9.8%)

0.008

Mortality, no./total no. (%)

32/238 (13%)

136/858 (15.9%)

0.42

  1. ARDS, acute respiratory distress syndrome; APACHE III, Acute Physiology Age Chronic Health Evaluation III; BMI, body mass index; ECMO, extra corporeal membrane oxygenation; ICU, intensive care unit; MV, mechanical ventilation