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Table 3 Comparisons of demographic data and clinical parameters between matched early, and late RRT groups (model 3)

From: Impact of timing of renal replacement therapy initiation on outcome of septic acute kidney injury

 

Early RRT (n= 178)

Late RRT (n= 178)

P-value

Demographic data

   

Age (years)

65.2 ± 15.6

66.7 ± 15.2

0.71

Male (%)

63.5

72.5

0.07

DM (%)

32.7

35.5

0.71

Hypertension (%)

47.8

46.6

0.83

CHF (%)

17.4

13.5

0.38

CKD (%)

28.1

20.2

0.06

Post-operative(%)

62.9

69.7

0.21

Admission creatinine (mg/dL)

1.9 ± 1.1

1.5 ± 1.0

0.07

   (mmol/L)

168.0 ± 97.2

132.6 ± 88.4

 

Mechanical ventilation(%)

85.4

89.3

0.34

Data at ICU admission

   

Hematocrit (%)

32.2 ± 12.1

32.1 ± 5.9

0.17

BUN (mg/dL)

50.8 ± 34.4

41.0 ± 30.4

0.07

   (mmol/L)

18.1 ± 12.2

14.6 ± 10.9

 

Creatinine (mg/dL)

2.9 ± 1.8

2.3 ± 1.6

0.13

   (μmol/L)

247.5 ± 159.1

200.7 ± 141.4

 

Albumin (g/dL)

2.9 ± 0.6

2.9 ± 0.7

0.13

   (g/L)

29 ± 6

29 ± 7

 

APACHE II scores

11.9 ± 6.8

10.7 ± 6.0

0.83

SOFA scores

8.9 ± 3.7

7.4 ± 3.8

0.61

SAPS III score

60.7 ± 12.3

62.2 ± 7.6

0.25

Pre-RRT data

   

Hematocrit (%)

30.0 ± 6.2

29.8 ± 0.6

0.19

BUN (mg/dL)

79.1 ± 41.4

84.0 ± 39.8

0.26

   (mmol/L)

28.3 ± 14.8

30.0 ± 14.2

 

Creatinine (mg/dL)

3.4 ± 1.9,

3.4 ± 0.8

0.25

   (μmol/L)

300.6 ± 168.0

299.7 ± 70.7

 

Albumin (g/dL)

3.1 ± 1.5

2.9 ± 0.6

0.10

   (g/L)

31 ± 15

29 ± 6

 

Potassium (mEq/L)

5.1 ± 1.0

4.3 ± 0.9

0.16

Lactate (mg/dL)

3.4 ± 3.6

3.1 ± 3.5

0.14

   (mmol/L)

0.4 ± 0.4

0.3 ± 0.4

 

GCS scores

11.7 ± 4.2

11.0 ± 4.5

0.40

Systolic blood pressure

123.5 ± 26.7

123.7 ± 25.7

0.37

Diastolic blood pressure

64.6 ± 54.3

60.1 ± 14.0

0.35

Central venous pressure

14.3 ± 5.7

13.4 ± 5.2

0.85

APACHE II scores

12.3 ± 6.7

14.0 ± 5.5

0.34

SOFA scores

10.9 ± 4.1

11.6 ± 3.7

0.13

SAPS III score

66.3 ± 6.8

68.6 ± 6.7

0.79

Hospital mortality (%)

70.8

69.7

0.98

  1. Values are presented as mean ± standard deviation or number (percentage) unless otherwise stated.
  2. APACHE II: Acute Physiology and Chronic Health Evaluation II; BUN: blood, urea, nitrogen; CHF: congestive heart failure; CKD: chronic kidney disease; DM: diabetes mellitus; GCS: Glasgow Coma Scale; RRT: renal replacement therapy; SAPS: Simplified Acute Physiology Score; SOFA: Sequential Organ Failure Assessment.