From: Impact of timing of renal replacement therapy initiation on outcome of septic acute kidney injury
 | Early RRT (n= 178) | Late RRT (n= 178) | P-value |
---|---|---|---|
Demographic data | Â | Â | Â |
Age (years) | 65.2 ± 15.6 | 66.7 ± 15.2 | 0.71 |
Male (%) | 63.5 | 72.5 | 0.07 |
DM (%) | 32.7 | 35.5 | 0.71 |
Hypertension (%) | 47.8 | 46.6 | 0.83 |
CHF (%) | 17.4 | 13.5 | 0.38 |
CKD (%) | 28.1 | 20.2 | 0.06 |
Post-operative(%) | 62.9 | 69.7 | 0.21 |
Admission creatinine (mg/dL) | 1.9 ± 1.1 | 1.5 ± 1.0 | 0.07 |
   (mmol/L) | 168.0 ± 97.2 | 132.6 ± 88.4 |  |
Mechanical ventilation(%) | 85.4 | 89.3 | 0.34 |
Data at ICU admission | Â | Â | Â |
Hematocrit (%) | 32.2 ± 12.1 | 32.1 ± 5.9 | 0.17 |
BUN (mg/dL) | 50.8 ± 34.4 | 41.0 ± 30.4 | 0.07 |
   (mmol/L) | 18.1 ± 12.2 | 14.6 ± 10.9 |  |
Creatinine (mg/dL) | 2.9 ± 1.8 | 2.3 ± 1.6 | 0.13 |
   (μmol/L) | 247.5 ± 159.1 | 200.7 ± 141.4 |  |
Albumin (g/dL) | 2.9 ± 0.6 | 2.9 ± 0.7 | 0.13 |
   (g/L) | 29 ± 6 | 29 ± 7 |  |
APACHE II scores | 11.9 ± 6.8 | 10.7 ± 6.0 | 0.83 |
SOFA scores | 8.9 ± 3.7 | 7.4 ± 3.8 | 0.61 |
SAPS III score | 60.7 ± 12.3 | 62.2 ± 7.6 | 0.25 |
Pre-RRT data | Â | Â | Â |
Hematocrit (%) | 30.0 ± 6.2 | 29.8 ± 0.6 | 0.19 |
BUN (mg/dL) | 79.1 ± 41.4 | 84.0 ± 39.8 | 0.26 |
   (mmol/L) | 28.3 ± 14.8 | 30.0 ± 14.2 |  |
Creatinine (mg/dL) | 3.4 ± 1.9, | 3.4 ± 0.8 | 0.25 |
   (μmol/L) | 300.6 ± 168.0 | 299.7 ± 70.7 |  |
Albumin (g/dL) | 3.1 ± 1.5 | 2.9 ± 0.6 | 0.10 |
   (g/L) | 31 ± 15 | 29 ± 6 |  |
Potassium (mEq/L) | 5.1 ± 1.0 | 4.3 ± 0.9 | 0.16 |
Lactate (mg/dL) | 3.4 ± 3.6 | 3.1 ± 3.5 | 0.14 |
   (mmol/L) | 0.4 ± 0.4 | 0.3 ± 0.4 |  |
GCS scores | 11.7 ± 4.2 | 11.0 ± 4.5 | 0.40 |
Systolic blood pressure | 123.5 ± 26.7 | 123.7 ± 25.7 | 0.37 |
Diastolic blood pressure | 64.6 ± 54.3 | 60.1 ± 14.0 | 0.35 |
Central venous pressure | 14.3 ± 5.7 | 13.4 ± 5.2 | 0.85 |
APACHE II scores | 12.3 ± 6.7 | 14.0 ± 5.5 | 0.34 |
SOFA scores | 10.9 ± 4.1 | 11.6 ± 3.7 | 0.13 |
SAPS III score | 66.3 ± 6.8 | 68.6 ± 6.7 | 0.79 |
Hospital mortality (%) | 70.8 | 69.7 | 0.98 |