| Baseline | Day 1 | Day 3 | Day 7 | ||||
---|---|---|---|---|---|---|---|---|
 | PHARLAP | Control | PHARLAP | Control | PHARLAP | Control | PHARLAP | Control |
V T , mls | 519 ± 56 | 501 ± 30 | 463 ± 42 | 563 ± 65 | 586 ± 58 | 511 ± 55 | 528 ± 76 | 579 ± 78 |
RR, bpm | 21 ± 2 | 21 ± 1 | 22 ± 2 | 20 ± 2 | 19 ± 2 | 24 ± 2 | 22 ± 2 | 22 ± 2 |
FiO 2 | 0.48 ± 0.06 | 0.57 ± 0.06 | 0.4 ± 0.04 | 0.5 ± 0.04 | 0.5 ± 0.07 | 0.55 ± 0.06 | 0.5 ± 0.07 | 0.5 ± 0.09 |
PEEP, cm H 2 O | 11.8 ± 0.7 | 14.2 ± 1.2 | 15 ± 1* | 10 ± 0.5 | 12.1 ± 1.5 | 9.3 ± 1.4 | 8.5 ± 1.8 | 7.8 ± 2.0 |
Pplateau, cmH 2 O | 28.4 ± 1.5 | 29 ± 1.5 | 27.6 ± 1.5 | 26.9 ± 1.4 | 24.2 ± 2.4 | 24 ± 2.1 | 21 ± 2.9 | 20. ± 3.4 |
Arterial pH | 7.34 ± 0.02 | 7.36 ± 0.02 | 7.36 ± 0.01 | 7.35 ± 0.01 | 7.38 ± 0.03 | 7.44 ± 0.03 | 7.42 ± 0.03 | 7.42 ± 0.04 |
PaCO 2 , mmHg | 49 ± 5 | 46 ± 5 | 45 ± 3 | 46 ± 3 | 47.6 ± 3.7 | 44 ± 3.5 | 43.3 ± 4 | 56.5 ± 5 |