Skip to main content

Table 3 Respiratory variables during seven days of treatment (mean ± SE) * P < 0

From: A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome

 

Baseline

Day 1

Day 3

Day 7

 

PHARLAP

Control

PHARLAP

Control

PHARLAP

Control

PHARLAP

Control

V T , mls

519 ± 56

501 ± 30

463 ± 42

563 ± 65

586 ± 58

511 ± 55

528 ± 76

579 ± 78

RR, bpm

21 ± 2

21 ± 1

22 ± 2

20 ± 2

19 ± 2

24 ± 2

22 ± 2

22 ± 2

FiO 2

0.48 ± 0.06

0.57 ± 0.06

0.4 ± 0.04

0.5 ± 0.04

0.5 ± 0.07

0.55 ± 0.06

0.5 ± 0.07

0.5 ± 0.09

PEEP,

cm H 2 O

11.8 ± 0.7

14.2 ± 1.2

15 ± 1*

10 ± 0.5

12.1 ± 1.5

9.3 ± 1.4

8.5 ± 1.8

7.8 ± 2.0

Pplateau, cmH 2 O

28.4 ± 1.5

29 ± 1.5

27.6 ± 1.5

26.9 ± 1.4

24.2 ± 2.4

24 ± 2.1

21 ± 2.9

20. ± 3.4

Arterial pH

7.34 ± 0.02

7.36 ± 0.02

7.36 ± 0.01

7.35 ± 0.01

7.38 ± 0.03

7.44 ± 0.03

7.42 ± 0.03

7.42 ± 0.04

PaCO 2 , mmHg

49 ± 5

46 ± 5

45 ± 3

46 ± 3

47.6 ± 3.7

44 ± 3.5

43.3 ± 4

56.5 ± 5

  1. Vt, tidal volume; RR, respiratory rate; FIO2, fraction of inspired oxygen; PEEP, positive end expiratory pressure; Pplateau, plateau pressure; PaCO2, partial pressure of carbon dioxide