Skip to main content

Table 3 Respiratory variables during seven days of treatment (mean ± SE) * P < 0

From: A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome

  Baseline Day 1 Day 3 Day 7
  PHARLAP Control PHARLAP Control PHARLAP Control PHARLAP Control
V T , mls 519 ± 56 501 ± 30 463 ± 42 563 ± 65 586 ± 58 511 ± 55 528 ± 76 579 ± 78
RR, bpm 21 ± 2 21 ± 1 22 ± 2 20 ± 2 19 ± 2 24 ± 2 22 ± 2 22 ± 2
FiO 2 0.48 ± 0.06 0.57 ± 0.06 0.4 ± 0.04 0.5 ± 0.04 0.5 ± 0.07 0.55 ± 0.06 0.5 ± 0.07 0.5 ± 0.09
PEEP,
cm H 2 O
11.8 ± 0.7 14.2 ± 1.2 15 ± 1* 10 ± 0.5 12.1 ± 1.5 9.3 ± 1.4 8.5 ± 1.8 7.8 ± 2.0
Pplateau, cmH 2 O 28.4 ± 1.5 29 ± 1.5 27.6 ± 1.5 26.9 ± 1.4 24.2 ± 2.4 24 ± 2.1 21 ± 2.9 20. ± 3.4
Arterial pH 7.34 ± 0.02 7.36 ± 0.02 7.36 ± 0.01 7.35 ± 0.01 7.38 ± 0.03 7.44 ± 0.03 7.42 ± 0.03 7.42 ± 0.04
PaCO 2 , mmHg 49 ± 5 46 ± 5 45 ± 3 46 ± 3 47.6 ± 3.7 44 ± 3.5 43.3 ± 4 56.5 ± 5
  1. Vt, tidal volume; RR, respiratory rate; FIO2, fraction of inspired oxygen; PEEP, positive end expiratory pressure; Pplateau, plateau pressure; PaCO2, partial pressure of carbon dioxide
\