Skip to main content

Table 2 Respiratory variables during the first 24 hrs of treatment (mean ± SE)

From: A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome

  1 hour 3 hours 6 hours 24 hours
  PHARLAP Control PHARLAP Control PHARLAP Control PHARLAP Control
VT, mls 519 ± 56 501 ± 30 517 ± 51 529 ± 58 529 ± 56 542 ± 49 463 ± 42 563 ± 65
RR, bpm 21 ± 2 21 ± 1 20 ± 2 21 ± 2 21 ± 2 21 ± 2 22 ± 2 20 ± 2
FIO2 0.47 ± 0.03 0.59 ± 0.04 0.5 ± 0.04 0.5 ± 0.03 0.4 ± 0.05 0.57 ± 0.05 0.4 ± 0.04 0.5 ± 0.04
PEEP, cm H2O 17.4 ± 1 11.6 ± 1 17.4 ± 1* 11 ± 0.5 16.7 ± 1* 10 ± 0.6 15 ± 1* 10 ± 0.5
Pplateau, cm H2O 28.9 ± 1.2 27.1 ± 1.2 28.3 ± 1.1 26.6 ± 1.1 29 ± 0.8 26 ± 0.8 27.6 ± 1.5 26.9 ± 1.4
Arterial pH 7.34 ± 0.02 7.36 ± 0.02 7.34 ± 0.02 7.34 ± 0.03 7.34 ± 0.02 7.36 ± 0.01 7.36 ± 0.01 7.35 ± 0.01
PaCO2, mm Hg 49 ± 5 46 ± 5 47 ± 4 48 ± 6 48 ± 3 45 ± 3 45 ± 3 46 ± 3
  1. *P < 0.05 for differences between PHARLAP and control groups.
  2. VT, tidal volume; RR, respiratory rate; FIO2, fraction of inspired oxygen; PEEP, positive end expiratory pressure; Pplateau, plateau pressure; PaO2/FIO2, partial pressure of oxygen to inspired fraction of oxygen ratio; PaCO2, partial pressure of carbon dioxide
\