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Table 2 Association of the area under the BG curve above 2 g/l with clinical characteristics and neuropathological findings

From: Hyperglycaemia and apoptosis of microglial cells in human septic shock

 

Spearman ρ (95%CI)

P

SAPS-II at admission

0.34 (-0.17 to 0.71)

0.18

Knauss

-0.21 (-0.63 to 0.30)

0.43

McCabe

0.05 (-0.44 to 0.52)

0.85

Neuropathological findings

  

Neuronal ischaemia

0.05 (-0.43 to 0.53)

0.82

Gliosis

0.15 (-0.36 to 0.59)

0.57

GFAP expression

0.11 (-0.39 to 0.56)

0.67

HLA-DR expression

0.06 (-0.43 to 0.53)

0.81

CD68 expression

0.44 (-0.05 to 0.76)

0.08

Beta-APP expression

0.61 (0.06 to 0.88)

0.03

Neuronal apoptosis

0.53 (0.07 to 0.81)

0.028

Microglial apoptosis

0.70 (0.33 to 0.88)

0.002

Glial TNFα expression

-0.04 (-0.51 to 0.45)

0.86

Endothelial iNOS expression

0.04 (-0.45 to 0.51)

0.87

  1. Each neuropathological finding was score from 0 to 3 (see methods). beta-APP, beta-amyloid precursor protein; CD68, Cluster of Differentiation; GFAP, glial fibrillary acidic protein; HLA-DR, Major Histocompatibility Complex Class II cell surface receptor; iNOS, inducible Nitric Oxide Synthase; TNFα, tumor necrosis factor alpha.