Table 1 Patients' characteristics
From: Hyperglycaemia and apoptosis of microglial cells in human septic shock
Whole population (n = 17) | |
|---|---|
Women (%) | 6 (35) |
Age (years) | 68 (53 to 72) |
Cerebrovascular risk factors (%) | 11 (65) |
Diabetes (%) | 4 (24) |
Medical admission | 11 (65) |
Site of infection | |
Lung only (%) | 9 (53) |
Abdominoperitoneal only (%) | 0 |
Urinary tract only (%) | 0 |
Cellulitis only (%) | 5 (29) |
> 1 site | 5 (18) |
Unknown | 0 |
Positive culture at any site (%) | |
Gram-positive only (%) | 4 (24) |
Gram-negative only (%) | 6 (35) |
Fungus only (%) | 0 |
Mixed (%) | 7 (411) |
Positive blood culture (%) | 4 (24) |
SAPS-II at admission | 43 (30 to 58) |
Highest OSF score during ICU stay | 4 (4 to 5) |
Duration of septic shock (days) | 4 (2 to 10) |
Cumulative time spent with MAP < 60 mm Hg (h) | 11 (4 to 25) |
Lowest SAP (mm Hg) | 57 (33 to 66) |
Lowest PaO2 (kPa) | 8.1 (6.1 to 9.0) |
Lowest SaO2 (%) | 85 (73 to 90) |
Highest blood sodium level (mmol/L) | 139 (135 to 149) |
Lowest blood sodium level (mmol/L) | 132 (128 to 137) |
Blood glucose level | |
Lowest BG (gr/l) | 0.6 (0.3 to 1.1) |
Highest BG (gr/l) | 3.5 (3.3 to 5.4) |
Δmax BG (gr/l) | 3.4 (2.1 to 4.8) |
Mean BG (gr/l) | 2.2 (1.4 to 2.8) |
Patients with hypoglycaemia (%) | 5 (29) |
Patients with hyperglycaemia (%) | 15 (88) |
Patients with prolonged hyperglycaemia (%) | 9 (53) |
Patients treated with insulin (%) | 6 (35) |
Neuronal apoptosis | 1.0 (1.0 to 2.0) |
Microglial apoptosis | 1.0 (1.0 to 1.5) |
GFAP expression | 2.0 (2.0 to 3.0) |
HLA-DR expression | 1.0 (1.0 to 2.0) |
CD68 expression | 1.0 (0.5 to 1.5) |
Glial TNF-α expression | 1.0 (0 to 1.0) |
iNOS expression | 1.0 (1.0 to 1.0) |
Neuronal GLUT4 | 1.5 (1.0 to 2.0) |
Microglial GLUT5 | 1.0 (0.5 to 1.0) |
CD68 | 1.5 (1.0 to 2.0) |
Beta-APP | 1.0 (1.0 to 1.5) |