Figure 1
From: Injurious mechanical ventilation affects neuronal activation in ventilated rats
Hemodynamic and respiratory characteristics of rats during the three-hour period. No differences between groups were observed at baseline. MAP remained stable in both groups. Pplateau and Crs increased significantly during HVt ventilation but remained stable during the three-hour period. There were no differences between LVt and HVt in Pa/FiO2. pH in animals spontaneously breathing was slightly higher than in animals receiving MV. PCO2 increased only in LVt animals. Data are presented as mean ± SE. *: P < 0.05 versus the HVt group, and #: P < 0.05 vs Spont group. N = 8 animals per group. Abbreviations: MAP, mean arterial pressure; BAS, basal; LVt, low tidal volume; HVt, high tidal volume; Spont, spontaneous breathing; Pplateau, plateau pressure; Crs, static compliance of the respiratory system.