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Table 2 Therapeutic interventions in the study populationa

From: Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study

Interventions

rhTM group (n = 20)

Control group (n = 45)

P value

Mechanical ventilation, %

20 (100)

45 (100)

n.s.

Shock, %

15 (75)

32 (71)

n.s.

Use of any vasopressor, %

13 (65)

33 (73)

n.s.

Infusion within 24 hours, mL

8,600 (6,400 to 13,500)

7,600 (4,200 to 11,500)

n.s.

Antibiotics administration within 3 hours of enrollment, %

20 (100)

45 (100)

n.s.

Appropriateness of antibiotic therapy, %

16 (80)

37 (82)

n.s.

Use of low-dose steroid, %

3 (15)

14 (31)

n.s.

Renal replacement therapy, %

9 (45)

16 (36)

n.s.

  1. arhTM, recombinant human soluble thrombomodulin; n.s., not significant. Data are expressed as group medians (interquartile range) or number (percent).