Interventions | rhTM group (n = 20) | Control group (n = 45) | P value |
---|---|---|---|
Mechanical ventilation, % | 20 (100) | 45 (100) | n.s. |
Shock, % | 15 (75) | 32 (71) | n.s. |
Use of any vasopressor, % | 13 (65) | 33 (73) | n.s. |
Infusion within 24 hours, mL | 8,600 (6,400 to 13,500) | 7,600 (4,200 to 11,500) | n.s. |
Antibiotics administration within 3 hours of enrollment, % | 20 (100) | 45 (100) | n.s. |
Appropriateness of antibiotic therapy, % | 16 (80) | 37 (82) | n.s. |
Use of low-dose steroid, % | 3 (15) | 14 (31) | n.s. |
Renal replacement therapy, % | 9 (45) | 16 (36) | n.s. |