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Table 1 Baseline characteristics and diagnostic data of the study populationa

From: Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study

Characteristics

rhTM group (n = 20)

Control group (n = 45)

P value

Age, yr

67.4 ± 2.9

65.4 ± 2.7

n.s.

Male sex, %

11 (55)

25 (55)

n.s.

APACHE II score

26.5 ± 1.4

21.2 ± 0.9

0.003

SOFA score

11.5 ± 0.5

9.7 ± 0.4

0.009

Number of dysfunctional organs, n

3.7 ± 0.3

3.0 ± 0.2

0.04

Positive blood culture, %

11 (55)

13 (29)

0.04

Site of infection

   

   Lung, %

2 (10)

3 (7)

n.s.

   Abdomen, %

8 (40)

25 (55)

 

   Urinary tract, %

6 (30)

4 (9)

 

   Other, %

4 (20)

13 (29)

 
  1. arhTM, recombinant human soluble thrombomodulin; n.s., not significant; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment. Data are expressed as group means ± standard error of the mean or number (percent).
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Critical Care

ISSN: 1364-8535