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Table 4 Donor kidney biopsy findings in the high and low NGAL groupsa

From: Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study

 

Serum NGAL

 

Urine NGAL

 

Biopsy findings

High, ≥214 ng/mL

(n = 38)

Low, < 214 ng/mL

( n = 57)

P value

High, ≥18 ng/mL

(n = 26)

Low, < 18 ng/mL

(n = 69)

P value

Tubulitis

0 (0%)

0 (0%)

NS

0 (0%)

0 (0%)

NS

Intimal arteritis

0 (0%)

0 (0%)

NS

0 (0%)

0 (0%)

NS

Interstitial inflammation

1 (2.6%)

0 (0%)

NS

1 (3.4%)

0 (0%)

NS

Glomerulitis

0 (0%)

0 (0%)

NS

0 (0%)

0 (0%)

NS

Interstitial fibrosis

3 (7.9%)

2 (3.5%)

NS

3 (10.3%)

2 (3.0%)

NS

Tubular atrophy

3 (7.9%)

3 (5.3%)

NS

3 (10.3%)

2 (3.0%)

NS

Glomerulopathy

3 (7.9%)

3 (5.3%)

NS

3 (10.3%)

2 (3.0%)

NS

Mesangial matrix increase

1 (2.6%)

0 (0%)

NS

1 (3.4%)

0 (0%)

NS

Intimal thickening

11 (28.9%)

14 (24.6%)

NS

9 (31.0)

15 (22.7%)

NS

Arterial hyalinosis

8 (21.1%)

13 (22.8%)

NS

8 (27.5%)

15 (22.7%)

NS

CADI score, n

      

   0 or 1

30

46

NS

17

61

0.010

   ≥2

8

11

 

9

8

 
  1. aCADI, Chronic Allograft Damage Index [31]; NGAL, neutrophil gelatinase-associated lipocalin.