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Table 3 Donor NGAL, donor kidney function and onset of graft function after transplantationa

From: Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study

Parameter High S-NGAL
(≥214 ng/mL)
Low S-NGAL
(< 214 ng/mL)
P value High U-NGAL
(≥18 ng/mL)
Low U-NGAL
(≥18 ng/mL)
P value
Donors, n 38 57   26 69  
Kidneys, n 69 99   52 116  
Mean donor plasma creatinine, μmol/L (± SD) 70 (22.8) 57 (± 15.1) 0.021 71 (± 21.8) 59 (± 17.8) 0.006
Mean donor eGFR, mL/min (± SD) 108 (33.9) 124 (± 34.5) 0.033 105 (± 31.2) 122 (± 35.7) 0.039
Prolonged DGF (n = 25) 12 (17.4%) 13 (13.1%)   12 (23.1%) 13 (11.2%)  
Short DGF (n = 41) 22 (31.9%) 19 (19.1%)   15 (28.8%) 26 (22.4%)  
EGF (n = 102) 35 (50.7%) 67 (67.8%) NS 25 (48.1%) 77 (66.4%) 0.028
Mean recipient 1-year plasma creatinine level, μmol/L (± SD) 117 (43.8) 115 (± 37.7) NS 114 (± 28.5) 117 (± 45.0) NS
Mean Recipient 1-year eGFR mL/min (± SD) 57 (16.9) 60 (± 21.1) NS 57 (± 15.9) 59 (± 21.4) NS
1-year patient survival 98.6% 99.0% NS 96% 100% NS
1-year graft survival 91.4% 98.0% 0.050 90.3% 97.4% 0.048
  1. aDGF, delayed graft function; EGF, early graft function; S-NGAL, serum neutrophil gelatinase-associated lipocalin; U-NGAL, urine neutrophil gelatinase-associated lipocalin.