Skip to main content

Table 2 Percentage and phenotype of monocyte subpopulations according to overt disseminated intravascular coagulation status and mortality

From: Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation

  

Non-overt DIC

Overt DIC

Survivors

Non-survivors

Number

 

67

31

76

22

Absolute monocyte count, × 106/L

 

510 (336-752)

699 (351-1,260)

496 (337-743)

883 (452-1,913)a

CD14brightCD16negative classic monocytes

Percentage

62.0 (48.3-70.9)

55.0 (48.4-65.6)

62.4 (51.1-70.7)

50.0 (39.2-54.5)a

 

Thrombomodulin

32.0 (23.9-41.9)

29.0 (23.2-52.1)

31.1 (22.5-40.6)

35.9 (24.9-75.8)a

 

Tissue factor

4.0 (3.4-4.5)

3.4 (2.6-4.4)b

4.0 (3.3-4.4)

3.5 (2.7-4.3)

CD14brightCD16positive inflammatory monocytes

Percentage

13.0 (7.7-18.9)

11.0 (7.1-19.0)

12.8 (7.7-18.8)

10.7 (5.9-18.9)

 

Thrombomodulin

55.0 (42.5-75.1)

70.0 (54.5-117.5)b

54.7 (43.1-71.9)

73.7 (60.5-125.5)a

 

Tissue factor

5.4 (4.2-7.1)

5.6 (4.7-6.5)

5.5 (4.2-7.1)

5.3 (4.7-6.3)

CD14dimCD16positive dendritic monocytes

Percentage

1.8 (0.8-4.4)

1.6 (1.0-3.2)

1.7 (0.8-3.6)

2.7 (1.0-6.2)

 

Thrombomodulin

92.5 (49.9-114.8)

71.6 (47.7-115.0)

85.2 (46.7-114.5)

71.9 (55.2-115.8)

 

Tissue factor

9.5 (5.1-20.7)

8.6 (6.1-16.2)

10.0 (5.2-19.4)

7.0 (5.9-17.0)

  1. aP < 0.05 between survivors and non-survivors. bP < 0.05 between non-overt disseminated intravascular coagulation (DIC) and overt DIC. The expression levels of thrombomodulin and tissue factor were scaled by an arbitrary unit of mean fluorescence intensity.