Table 3 Antimicrobials received in the ICU within the seven days prior to VAP onset
Antimicrobials | PSPA-VAP (n= 153) | PRPA-VAP (n= 70) | P-value |
|---|---|---|---|
Penicillin | 63 (41) | 21 (30) | 0.27 |
Cephalosporins 1, 2 or 3 | 46 (30) | 22 (31) | 0.99 |
Ceftazidime | 7 (5) | 3 (4) | 0.99 |
Cephalosporins 4 (cefepim, cefpirome) | 4 (3) | 5 (7) | 0.19 |
Piperacillin-Tazobactam | 14 (9) | 13 (19) | 0.01 |
Ureidopenicillin - carboxypenicillin | 20 (13) | 22 (31) | 0.0004 |
Tazobactam, sulbactam or Clavulanic acid | 56 (37) | 26 (37.1) | 0.41 |
Penems | 11 (7) | 6 (8.6) | 0.92 |
Fluoroquinolones | 20 (13) | 17 (24.3) | 0.058 |
Aminoglycosides | 38 (25) | 21 (30) | 0.24 |
Azoles | 16 (10) | 13 (19) | 0.14 |
Glycopeptides | 24 (16) | 14 (20) | 0.42 |
Other | 14 (9) | 8 (11) | 0.99 |
At least one antimicrobial | 101 (66) | 44 (63) | 0.60 |