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Table 1 Demographic data and baseline characteristics of study population.

From: Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients

 

Non-carrier

TLR2 SNP

TLR4 SNP

P-value

Number, n

274

13

51

 

Gender (M/F)

200/74

8/5

38/13

0.6236

Age, yr (median (IQR))

69 (62 to 75)

74 (66 to 77)

71 (61 to 77)

0.1944

Weight, kg (median (IQR))

80 (70 to 90)

80 (70 to 93)

80 (70 to 90)

0.7685

Height, m (median (IQR))

1.72 (1.65 to 1.76)

1.68 (1.65 to 1.72)

1.73 (1.66 to 1.78)

0.2200

Time of surgery, h

4.0 (3.4 to 4.7)

3.8 (3.3 to 4.1)

3.8 (3.3 to 4.4)

0.2101

Diabetes mellitus, n (%)

96 (35)

5 (38)

12 (24)

0.2375

Admission medication

    

   Beta-blocker, n (%)

215 (78)

13 (100)

35 (69)

0.0362

   ACE inhibitor, n (%)

137 (50)

10 (77)

30 (59)

0.1048

   Calcium channel-blocker, n (%)

39 (14)

4 (31)

4 (8)

0.0862

   Diuretics, n (%)

138 (50)

5 (38)

25 (49)

0.7455

   Nitrates, n (%)

68 (25)

3 (23)

11 (22)

0.9285

Type of surgery

    

   CABG, n (%)

183 (67)

9 (69)

36 (71)

 

   VS, n (%)

33 (12)

3 (23)

4 (8)

0.7542

   CABG + VS, n (%)

43 (16)

1 (8)

7 (14)

 

   Other, n (%)

15 (6)

0 (0)

4 (8)

 

28-day outcome

    

   Survivor, n (%)

247 (93)

9 (75)

41 (89)

0.0753

   Nonsurvivor, n (%)

19 (7)

3 (25)

5(11)

 
  1. CABG, coronary artery bypass graft; IQR, interquartile range; TLR2 SNP, toll-like receptor2 single-nucleotide polymorphism carrier; TLR4 SNP, toll-like receptor4 single-nucleotide polymorphism carrier; VS, valve surgery.