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Table 2 Baseline characteristics and outcomes of PMV and non-PMV cases in study population

From: Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit

 

n*

   
 

PMV

Non-PMV

PMV

Non-PMV

P value

Age mean (SD)

349

7,499

59.6 (15.2)

56.9 (18.1)

0.001

Sex n (% female)

349

7,499

148 (42.4)

3,218 (42.9)

0.86

Days in hospital before ICU admission

    

<0.001a

   Mean (SD)

  

5.9 (14.0)

3.5 (11.0)

 

   Median (IQR)

  

1 (0 to 5)

0 (0 to 2)

 

APACHE II score mean (SD)

307

6,659

21.0 (6.8)

18.8 (8.3)

<0.001

CPR in 24 hours before ICU admission n (%)

349

7,499

23 (6.6)

663 (8.8)

0.15

Number of co-morbidities n (%)

340

7,228

  

<0.001a

   None

  

276 (81.2)

5,317 (73.6)

 

   1

  

50 (14.7)

1,211 (16.8)

 

   2 or more

  

14 (4.1)

700 (9.7)

 

Surgical status n (%)

347

7,463

  

<0.001

   Emergency

  

52 (15.0)

1,747 (23.4)

 

   Elective

  

15 (4.3)

893 (12.0)

 

   Non-surgical

  

280 (80.7)

4,823 (64.6)

 

Ventilated on day 1 n (%)

341

7,354

312 (91.5)

4,884 (66.4)

<0.001

PaO2:FiO2 ratio (mmHg)

334

6,477

  

<0.001

   Mean (SD)

  

155 (82)

242 (125)

 

   Median (IQR)

  

139 (93 to 201)

227 (142 to 322)

 

Tracheostomy placed during admission n (%)

349

7,499

219 (62.8)

470 (6.3)

<0.001

Five most common admission diagnoses n (%)

349

7,499

  

-

   Pneumonia - any cause

  

92 (26.4)

650 (8.7)

 

   Septic shock - any source

  

39 (11.2)

398 (5.3)

 

   Trauma

  

22 (6.3)

466 (6.2)

 

   Gastrointestinal perforation

  

18 (5.2)

-

 

   Pancreatitis

  

18 (5.2)

-

 

   Cardiac arrest

  

-

457 (6.1)

 

   Self-inflicted overdose

  

-

401 (5.3)

 

Length of ICU stay (days)

349

7,499

  

-

   Mean (SD)

  

37.2 (16.1)

3.8 (4.9)

 

   Median (IQR)

  

33 (26 to 44)

2 (1 to 5)

 

Number of days ventilated

349

7,499

  

-

   Mean (SD)

  

33.2 (14.7)

2.9 (4.2)

 

   Median (IQR)

  

29 (24 to 38)

1 (0 to 3)

 

Length of hospital stay after ICU discharge (days)

296

6,709

  

<0.001a

   Mean (SD)

  

35 (49)

19 (40)

 

   Median (IQR)

  

17 (0 to 45)

7 (0 to 20)

 

Hospital discharge destination of survivors n (%)

179

4,436

  

0.06

   Normal residence

  

160 (89.4)

4,155 (93.7)

 

   Rehabilitation unit

  

14 (7.8)

224 (5.0)

 

   Long-term institutional care

  

5 (2.8)

49 (1.1)

 

   Hospice or equivalent

  

0 (0)

5 (0.1)

 

ICU mortality n (%)

317

7,103

83 (26.2)

1,654 (23.3)

0.23

Hospital mortality n (%)

305

6,763

123 (40.3)

2,286 (33.8)

0.02

  1. Readmission episodes are excluded (n = 428) for length of hospital stay, hospital discharge destination, ICU mortality and hospital mortality. *Due to missing data, n is stated for each variable. aMann-Whitney U test.
  2. APACHE, Acute Physiology and Chronic Health Evaluation; CPR, cardiopulmonary resuscitation; FiO2, fraction of inspired oxygen; IQR, interquartile range; PaO2, partial pressure of arterial oxygen in mmHg; PMV, prolonged mechanical ventilation; SD, standard deviation.
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