Table 2 Demographic and clinical parameters of survivors and non-survivors patients with severe sepsis
From: Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis
Survivors (n= 124) | Nonsurvivors (n= 62) | P | |
|---|---|---|---|
Female sex * | 39 (31.5) | 25 (40.3) | 0.25 |
Age (years) † | 55 (45 to 68) | 63 (51 to 72) | 0.19 |
Diabetes mellitus * | 25 (20.2) | 23 (37.1) | 0.02 |
COPD * | 19 (15.3) | 9 (14.5) | 0.99 |
Statins previous to sepsis diagnosis* | 27 (21.8) | 16 (25.8) | 0.58 |
Ischemic heart disease* | 14 (11.3) | 7 (11.3) | 0.99 |
Site of infection | 0.90 | ||
Respiratory * | 64 (51.6) | 36 (58.0) | |
Abdominal * | 29 (23.4) | 13 (21.0) | |
Other sites* | 31 (25.0) | 13 (21.0) | |
Source of sepsis | 0.73 | ||
Community* | 93 (75.0) | 49 (79.0) | |
Nosocomial extra-ICU* | 12 (9.7) | 7 (11.3) | |
Nosocomial intra-ICU* | 19 (15.3) | 6 (9.7) | |
Pa02/FI02 ratio † | 162 (107 to 260) | 164 (96 to 228) | 0.18 |
Creatinine (mg/dl) † | 1.2 (0.8 to 1.9) | 1.4 (0.9 to 2.8) | 0.06 |
Bilirubin (mg/dl) † | 0.9 (0.6 to 1.6) | 0.9 (0.5 to 2.0) | 0.64 |
Leukocytes/mm3 † | 14200 (9200 to 18700) | 15850 (9050 to 22525) | 0.34 |
Lactatemia (mmol/L) † | 1.7 (1.0 to 3.5) | 3.9 (1.3 to 6.7) | <0.001 |
Platelet count*103/mm3 † | 199 (136 to 270) | 139 (79 to 218) | 0.002 |
APACHE-II score † | 19 (14 to 23) | 23 (18 to 29) | <0.001 |
SOFA score † | 9 (7 to 11) | 12 (9 to 14) | <0.001 |
Mechanical ventilation* | 102 (82.3) | 58 (93.5) | 0.04 |
Septic shock* | 105 (84.7) | 57 (91.9) | 0.24 |
sCD40L (ng/ml) † | 3.78 (2.51 to 5.38) | 4.42 (3.05 to 6.09) | 0.04 |
Tissue factor (pg/ml) † | 123 (99 to 163) | 120 (96 to 150) | 0.56 |
TNF-alpha (pg/ml) † | 32 (20 to 50) | 39 (18 to 79) | 0.38 |
IL-10 (pg/ml) † | 10 (6 to 36) | 53 (7 to 169) | <0.001 |