Admission | Day 1 | Day 2 | Day 3 | Day 5 | Day 7 | P(†) | |
---|---|---|---|---|---|---|---|
IL-6 | P = 0.0001 | ||||||
Placebo | 489.7 (83.5 to 2700) | 219 (54 to 691) | 77.5 (35.9 to 266.7) | 48 (17.5 to 136) | 37 (15.2 to 104.2) | 23.9 (10.2 to 77.4) | |
MPDN | 1060 (143.7 to 2594) | 40.6 (20.8 to 132) | 12.2 (0 to 36.4) | 11.3 (0 to 34) | 9 (0 to 23) | 0.5 (0 to 23) | |
IL-8 | P = 0.01 | ||||||
Placebo | 118 (28.1 to 253) | 48.6 (19.9 to 196) | 38.8 (16.1 to 92) | 20.3 (12 to 103) | 22.5 (9.5 to 66.9) | 14 (0 to 55.2) | |
MPDN | 134 (68.2 to 226) | 32.3 (19.5 to 75) | 13.7 (7.4 to 35) | 14.6 (5.8 to 24) | 11.3 (6.2 to 23.8) | 11 (0 to 53) | |
IL-10 | ns | ||||||
Placebo | 9.9 (0 to 62.2) | 0 (0 to 11.2) | 0 (0 to 4) | 0 (0 to 5) | 0 (0 to 3.7) | 0 (0 to 2.7) | |
MPDN | 14.8 (0 to 35.2) | 0 (0 to 6) | 0 (0 to 5) | 0 (0 to 0) | 0 (0 to 0) | 0 (0 to 0) |