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Table 3 Main outcome variables

From: Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial

 

Placebo

MPDN

P

Need for mechanical ventilation

   

   Conventional mechanical ventilation (‡)

3

0

ns

   Non-invasive positive pressure ventilation (‡)

2

1

ns

   Mechanical ventilation total (‡)

5

1

ns

   Duration of mechanical ventilation (days):

   

- Conventional * (†)

10 (13 to 19.5)

-

ns

- NPPV * (†)

16.5 (6 to 27)

3

ns

- Total * (†)

13 (7 to 26)

3

ns

ICU admission

5

4

ns

   Duration of ICU stay, days (†)

10.5 (6.25 to 24.5)

6.5 (5.5 to 9)

ns

   <24 hours (‡)

3

3

ns

   >24 hours (‡)

2

1

ns

   Development of shock (‡)

2

1

ns

Mortality

   

   Early ( ≤ 9 days) (‡)

-

1

ns

   Late (>9 days) (‡)

1

0

ns

General ward stay (†)

11.5 (9 to 14)

10 (9 to 13)

ns

Total hospital stay (†)

12 (9 to 18)

10 (9 to 13)

ns

Time to resolution of morbidity (†)

7 (3 to 10)

5 (2 to 6)

0.02

  1. *median and interquartile range; ns:no statistical significance (p > 0.05).
  2. (†) non paparametric Mann-Whitney U test.
  3. (‡) Fisher exact two-tailed test *median and interquartile range.
  4. ICU, intensive care unit; MPDN, methyl-prednisolone; NPPV, non-invasive positive pressure ventilation.