TY - JOUR AU - Curry, Nicola AU - Hopewell, Sally AU - Dorée, Carolyn AU - Hyde, Chris AU - Brohi, Karim AU - Stanworth, Simon PY - 2011 DA - 2011/03/09 TI - The acute management of trauma hemorrhage: a systematic review of randomized controlled trials JO - Critical Care SP - R92 VL - 15 IS - 2 AB - Worldwide, trauma is a leading cause of death and disability. Haemorrhage is responsible for up to 40% of trauma deaths. Recent strategies to improve mortality rates have focused on optimal methods of early hemorrhage control and correction of coagulopathy. We undertook a systematic review of randomized controlled trials (RCT) which evaluated trauma patients with hemorrhagic shock within the first 24 hours of injury and appraised how the interventions affected three outcomes: bleeding and/or transfusion requirements; correction of trauma induced coagulopathy and mortality. SN - 1364-8535 UR - https://doi.org/10.1186/cc10096 DO - 10.1186/cc10096 ID - Curry2011 ER -