Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest

Table 6 Multiple regression models for in-hospital mortality and survival time using an APACHE III-based marker of severity^a

Variable	Hospital mortality OR (95% CI)	P value	Time to death HR (95% CI)	P value
AP3no-ox^b	1.5 (1.5 to 1.6)	<0.0001	1.2 (1.2 to 1.2)	<0.0001
Treatment limitation^c	5.3 (3.8 to 7.2)	<0.0001	1.7 (1.5 to 1.8)	<0.0001
Year of admission	0.9 (0.9 to 0.9)	<0.0001	0.97 (0.96 to 0.98)	<0.0001
Lowest glucose in first 24 hours	1.1 (1.1 to 1.1)	<0.0001	1.02 (1.02 to 1.03)	<0.0001
Hospital admission from home	1.3 (1.1 to 1.4)	0.0002	1.1 (1.0 to 1.1)	0.02
Hypoxia/poor O₂ exchange versus normoxia	1.2 (1.1 to 1.4)	0.002	1.1 (1.0 to 1.2)	0.01
Hyperoxia versus normoxia	1.2 (1.0 to 1.5)	0.04	1.1 (1.0 to 1.2)	0.20

^aAPACHE III, Acute Illness Severity and Chronic Health Evaluation III; OR, odds ratio; 95% CI, 95% confidence interval; HR, hazard ratio; AP3no-ox, APACHE III score with oxygenation component removed; ^bAPACHE III risk of death with oxygen component removed from calculation algorithm; ^ctreatment limitation order or palliative care coded for the patient. Indigenous status was removed from both models for nonsignificance (P < 0.01): (OR 1.3 (95% CI, 1.0 to 1.8), P = 0.04), (HR 1.1 (95% CI, 0.9 to 1.1) P = 0.89).

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