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Table 1 Clinical and laboratory characteristics of severe pneumonia patients infected with the 2009 H1N1 virus, with and without corticosteroid treatment

From: Early corticosteroid treatment for severe pneumonia caused by 2009 H1N1 influenza virus

Group With steroids (n = 17) Without steroids (n = 15) P value
Clinical characteristics    
   Mean age, years 6.6 ± 1.5 7.8 ± 3.4 NS
   Males/Females, number 13/4 12/3 NS
   Duration of fever, days    
Before admission 1.3 ± 0.5 1.3 ± 0.6 NS
Total 2.1 ± 0.8 5.8 ± 4.8 0.009
   Hospitalization, days 6.4 ± 1.1 8.5 ± 7.0 NS
   Oxygen treatment, days 2.5 ± 0.6 5.1 ± 4.6 0.04
   Oseltamivir for less than 48 hours, number (percentage)a 17 (100) 13 (93) NS
   Pneumonia, number (percentage)    
Segmental/Lobar 12 (71) 13 (87) NS
Progression after admission 5 (29) 4 (27) NS
   Intensive care unit care, number (percentage) 0 (0) 4 (27) 0.02
   ARDS with ventilator, number (percentage) 0 (0) 2 (13) NS
   Resolution of pneumonia, number (percentage)b 15 (88) 7 (43) 0.01
Laboratory findings    
   Hemoglobin, g/dL 13.1 ± 1.0 13.2 ± 1.1 NS
   Leukocyte, × 109/L 11.8 ± 3.6 12.0 ± 5.0 NS
Neutrophil, percentage 83.8 ± 8.0 86.2 ± 12.9 NS
Lymphocyte, percentage 8.8 ± 6.3 7.4 ± 7.5 NS
Monocyte, percentage 6.0 ± 2.3 5.0 ± 3.8 NS
   Platelet, × 109/L 268 ± 74 246 ± 53 NS
   C-reactive protein, mg/dL 3.0 ± 3.1 4.6 ± 3.9 NS
   Erythrocyte sedimentation rate, mm/hour 14 ± 8 15 ± 12 NS
  1. Values are presented as mean ± standard deviation unless indicated otherwise. Laboratory findings were obtained at presentation. aNumber (percentage) of patients who received oseltamivir treatment within 48 hours of fever onset. bNumber (percentage) of patients who showed complete resolution of pneumonic infiltrations at discharge. ARDS, acute respiratory distress syndrome; NS, statistically non-specific.