Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy

Table 1 Inclusion criteria

	Fibrinogen-PCC group (Salzburg Trauma Centre)	FFP group (TR-DGU)
Type of therapy	ROTEM-guided administration of coagulation factor concentrates	According to local protocols
ISS	≥ 16
AIS thorax, abdomen, extremities	At least in one region, one injury with severity degree ≥3, AIS_head/neck < 5
Age (years)	18-70
Base deficit at admission	≥2 mmol/L
FFP administered	No FFP	≥2 units FFP
Fibrinogen/PCC administered	≥1 g fibrinogen; ≥ 500 U PCC	No fibrinogen or PCC
Investigated time period	2005-2009	2005-2008
Patients included in database	353	21263
Patients fulfilling inclusion criteria	80	601

AIS, abbreviated injury scale; FFP, fresh frozen plasma; ISS, injury severity score; n, number of patients; PCC, prothrombin complex concentrate; ROTEM, thromboelastometry; TR-DGU, trauma registry of the German Society for Trauma Surgery.

ISSN: 1364-8535